# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA904815 | B | Inhibition of Brucella suis histidinol dehydrogenase | Brucella suis | 15 | ALA1143663 | single protein format | Scientific Literature | |
2. | ALA965784 | F | Antibacterial activity against Brucella suis 1330 in minimal medium at 100 uM after 96 hrs | Brucella suis | 5 | ALA1153840 | organism-based format | Scientific Literature | |
3. | ALA955159 | F | Antibacterial activity against Brucella suis 1330 in minimal medium after 96 hrs | Brucella suis | 4 | ALA1153840 | organism-based format | Scientific Literature | |
4. | ALA955160 | F | Antibacterial activity against Brucella suis 1330 assessed as reduction in bacterial growth in minimal medium after 96 hrs relative to control | Brucella suis | 15 | ALA1153840 | organism-based format | Scientific Literature | |
5. | ALA955161 | B | Inhibition of Brucella suis histidinol dehydrogenase | Brucella suis | 15 | ALA1153840 | single protein format | Scientific Literature | |
6. | ALA955162 | F | Effect on Brucella suis 1330 growth in tryptic soy broth medium at 100 uM after 96 hrs | Brucella suis | 15 | ALA1153840 | organism-based format | Scientific Literature | |
7. | ALA955163 | F | Growth inhibition of Brucella suis 1330 in minimal medium containing 1 mM histidine at 100 uM after 96 hrs | Brucella suis | 1 | ALA1153840 | organism-based format | Scientific Literature | |
8. | ALA955164 | F | Growth inhibition of Brucella suis 1330 in minimal medium devoid of 1 mM histidine at 100 uM after 96 hrs | Brucella suis | 1 | ALA1153840 | organism-based format | Scientific Literature | |
9. | ALA955165 | F | Antibacterial activity against Brucella suis 1330 expressing hisD::Tn5 mutant in minimal medium containing 1 mM histidine after 96 hrs | Brucella suis | 1 | ALA1153840 | organism-based format | Scientific Literature | |
10. | ALA955166 | F | Inhibition of intracellular replication of Brucella suis 1330 in human THP1 cells assessed as reduction in number of viable intracellular bacteria at 25 uM treated 90 mins postinfection measured 24 hrs postinfection relative to control | Brucella suis | 5 | ALA1153840 | organism-based format | Scientific Literature | |
11. | ALA955167 | F | Antibacterial activity against Brucella suis 1330 assessed as reduction in bacterial intramacrophagic multiplication in human THP1 cells at 25 uM treated 90 mins postinfection measured 24 hrs postinfection relative to control | Brucella suis | 4 | ALA1153840 | organism-based format | Scientific Literature | |
12. | ALA955168 | F | Antibacterial activity against Brucella suis 1330 in minimal medium assessed as appearance of spontaneously drug-resistant mutants at 100 uM after 18 days of growth in solid medium | Brucella suis | 3 | ALA1153840 | organism-based format | Scientific Literature | |
13. | ALA955169 | T | Toxicity against human THP1 cells at 25 uM after 48 hrs by trypan blue exclusion method | Homo sapiens | 4 | ALA1153840 | cell-based format | Scientific Literature | |
14. | ALA3082924 | B | Ratio of histidinol IC50 to compound IC50 for Brassica oleracea (cabbage) histidinol dehydrogenase | Brassica oleracea | 2 | ALA3046189 | single protein format | Scientific Literature | |
15. | ALA3082926 | B | Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometry | Brassica oleracea | 12 | ALA3046189 | single protein format | Scientific Literature |