# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1050681 | Binding | Displacement of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureido)-1H-pyrazol-1-yl)phenylamino)acetamide) from inactive form of p38alpha expressed in Escherichia coli BL21(DE3) cells by enzyme fragment complementation assay | 30 | ALA1156773 | cell-based format | Scientific Literature | ||
2. | ALA1050682 | Binding | Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assay | 30 | ALA1156773 | cell-based format | Scientific Literature | ||
3. | ALA997159 | Binding | Inhibition of wild type chicken N-terminal His-tagged cSrc expressed in Escherichia coli BL21 (DE3) | Gallus gallus | 9 | ALA1136966 | assay format | Scientific Literature | |
4. | ALA997160 | Binding | Inhibition of chicken N-terminal His-tagged cSrc T338M mutant expressed in Escherichia coli BL21 (DE3) | Gallus gallus | 6 | ALA1136966 | assay format | Scientific Literature | |
5. | ALA997163 | Binding | Activity of wild type chicken c N-terminal His-tagged Src expressed in Escherichia coli BL21 (DE3) | Gallus gallus | 6 | ALA1136966 | assay format | Scientific Literature | |
6. | ALA997164 | Binding | Activity of human N-terminal His-tagged p38alpha expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 9 | ALA1136966 | assay format | Scientific Literature | |
7. | ALA997166 | Functional | Inhibition of cSrc in human PC3 cells assessed as reduction of phosphorylated Src Y416 level at 1 to 10 uM after 5 hrs by immunoblot | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
8. | ALA997168 | Functional | Inhibition of cSrc in human DU145 cells assessed as reduction of phosphorylated Src Y416 level at 1 to 10 uM after 5 hrs by immunoblot | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
9. | ALA997170 | Functional | Inhibition of cSrc in human PC3 cells assessed as reduction of phosphorylated FAK Y576/Y577 level at 1 to 10 uM after 5 hrs by immunoblot | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
10. | ALA997172 | Functional | Inhibition of cSrc in human DU145 cells assessed as reduction of phosphorylated FAK Y576/Y577 level at 1 to 10 uM after 5 hrs by immunoblot | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
11. | ALA997174 | Functional | Inhibition of human PC3 cell adhesion at 10 uM after 5 hrs by light microscopy | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
12. | ALA997176 | Functional | Inhibition of human DU145 cell adhesion at 10 uM after 5 hrs by light microscopy | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
13. | ALA997178 | Functional | Antiproliferative activity against human PC3 cells assessed as reduction of cell count at 1 to 10 uM after 5 hrs | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
14. | ALA997180 | Functional | Antiproliferative activity against human DU145 cells assessed as reduction of cell count at 1 to 10 uM after 5 hrs | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
15. | ALA997181 | Functional | Increase in cSrc expression in human PC3 cells after 5 hrs by immunoblot | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
16. | ALA997182 | Functional | Increase in cSrc expression in human DU145 cells after 5 hrs by immunoblot | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
17. | ALA999796 | Functional | Inhibition of cSrc in human PC3 cells assessed as effect on total FAK level at 1 to 10 uM after 5 hrs by immunoblot | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
18. | ALA995337 | Functional | Inhibition of cSrc in human DU145 cells assessed as effect on total FAK level at 1 to 10 uM after 5 hrs by immunoblot | Homo sapiens | 1 | ALA1136966 | cell-based format | Scientific Literature | |
19. | ALA995338 | Binding | Binding affinity to acrylodan-labeled cSrc assessed as dissociation half life at 100 nM | 5 | ALA1136966 | single protein format | Scientific Literature | ||
20. | ALA2406228 | Binding | Inhibition of cKIT V559D/T670I double mutant (unknown origin)-mediated phosphorylation of biotinylated poly-Glu-Tyr preincubated for 30 to 60 mins prior to substrate addition by TR-FRET assay | Homo sapiens | 15 | ALA2401695 | single protein format | Scientific Literature |