| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1004967 | B | Binding affinity to kappa opioid receptor in guinea pig brain membrane | Cavia porcellus | 1 | ALA1136971 | cell membrane format | Scientific Literature | |
| 2. | ALA1004968 | B | Binding affinity to mu opioid receptor in guinea pig brain membrane | Cavia porcellus | 1 | ALA1136971 | cell membrane format | Scientific Literature | |
| 3. | ALA1004969 | B | Binding affinity to delta opioid receptor in guinea pig brain membrane | Cavia porcellus | 1 | ALA1136971 | cell membrane format | Scientific Literature | |
| 4. | ALA1000642 | B | Ratio of IC50 for mu opioid receptor in guinea pig brain membrane to IC50 for kappa opioid receptor in guinea pig brain membrane | Cavia porcellus | 1 | ALA1136971 | cell membrane format | Scientific Literature | |
| 5. | ALA1000643 | F | Antagonist activity at kappa opioid receptor in rabbit vas deferens assessed as reversal of asimadoline-suppressed electrically-stimulated twitch response | Oryctolagus cuniculus | 1 | ALA1136971 | tissue-based format | Scientific Literature | |
| 6. | ALA1000644 | B | Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assay | Homo sapiens | 22 | ALA1136971 | cell-based format | Scientific Literature | |
| 7. | ALA1000645 | B | Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assay | Homo sapiens | 22 | ALA1136971 | cell-based format | Scientific Literature | |
| 8. | ALA1000646 | B | Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assay | Homo sapiens | 22 | ALA1136971 | cell-based format | Scientific Literature | |
| 9. | ALA1000647 | B | Ratio of Ki for human cloned mu opioid receptor to Ki for human cloned kappa opioid receptor | Homo sapiens | 13 | ALA1136971 | assay format | Scientific Literature | |
| 10. | ALA1000648 | F | Antagonist activity at human cloned kappa opioid receptor assessed as inhibition of 50 nM U50488H-stimulated GTPgammaS binding by cell based assay | Homo sapiens | 22 | ALA1136971 | cell-based format | Scientific Literature | |
| 11. | ALA1000649 | F | Antagonist activity at human cloned mu opioid receptor assessed as inhibition of 100 nM loperamide-stimulated GTPgammaS binding by cell based assay | Homo sapiens | 22 | ALA1136971 | cell-based format | Scientific Literature | |
| 12. | ALA2327125 | F | Antinociceptive activity in icv dosed C57B1/6J mouse assessed as tail withdrawal latency measured in every 10 mins for 1 hr by warm water tail withdrawal assay | Mus musculus | 1 | ALA2321730 | organism-based format | Scientific Literature | |
| 13. | ALA2327131 | B | Displacement of [3H]DAMGO from rat cloned MOR expressed in CHO cells after 90 mins by scintillation counting analysis | Rattus norvegicus | 2 | ALA2321730 | cell-based format | Scientific Literature | |
| 14. | ALA2327132 | B | Displacement of [3H]DPDPE from mouse cloned DOR expressed in CHO cells after 90 mins by scintillation counting analysis | Mus musculus | 2 | ALA2321730 | cell-based format | Scientific Literature | |
| 15. | ALA2327133 | B | Displacement of [3H]diprenorphine from rat cloned KOR expressed in CHO cells after 90 mins by scintillation counting analysis | Rattus norvegicus | 2 | ALA2321730 | cell-based format | Scientific Literature | |
| 16. | ALA2327845 | B | Displacement of DAGO from MOR in guinea pig brain membrane fraction after 30 mins by scintillation counting analysis | Cavia porcellus | 1 | ALA2321730 | cell membrane format | Scientific Literature | |
| 17. | ALA2327846 | B | Displacement of DPDPE from DOR in guinea pig brain membrane fraction after 30 mins by scintillation counting analysis | Cavia porcellus | 1 | ALA2321730 | cell membrane format | Scientific Literature | |
| 18. | ALA2327847 | B | Displacement of [3H]Cl-977 from KOR in guinea pig brain membrane fraction after 30 mins by scintillation counting analysis | Cavia porcellus | 1 | ALA2321730 | cell membrane format | Scientific Literature | |
| 19. | ALA2404504 | F | Prevention of cocaine-induced reinstatement of extinguished cocaine seeking behavior in C57BL/6J mouse at 30 to 60 mg/kg, po qd for 2 days followed by additional cycle of cocaine place conditioning at 30 mins post last dose measured on day 3 | Mus musculus | 1 | ALA2401730 | organism-based format | Scientific Literature | |
| 20. | ALA2404505 | F | Prevention of stress-induced reinstatement of extinguished cocaine cocaine seeking behavior in C57BL/6J mouse at 30 mg/kg, po qd for 2 days measured 3 hrs post last dose by forced swim test | Mus musculus | 1 | ALA2401730 | organism-based format | Scientific Literature |
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