| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA973872 | F | Cicatrizant activity against mouse measured by wound breaking strength at 50 mg/ml administered every 12 hrs measured after 48 hrs relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA973877 | F | Cicatrizant activity against mouse assessed as wound breaking strength per gram of body weight administered every 12 hrs measured after 48 hrs relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA3586934 | F | Antileishmanial activity against Leishmania infantum MHOM/ES/2007/DP532JFJ infected in mouse BMDM cells assessed as reduction in intracellular amastigotes after 48 hrs | Leishmania infantum | 3 | organism-based format | Scientific Literature | ||
| 4. | ALA3586935 | F | Antileishmanial activity against Leishmania donovani MHOM/IN/00/LEM138 infected in mouse BMDM cells assessed as reduction in intracellular amastigotes after 48 hrs | Leishmania donovani | 3 | organism-based format | Scientific Literature | ||
| 5. | ALA3586936 | A | Cytotoxicity against mouse L929 cells after 72 hrs by trypan blue assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA3586937 | F | Selectivity index, ratio of CC50 for mouse L929 cells to IC50 for Leishmania infantum MHOM/ES/2007/DP532JFJ | 3 | cell-based format | Scientific Literature | |||
| 7. | ALA3586938 | F | Selectivity index, ratio of CC50 for mouse L929 cells to IC50 for Leishmania donovani MHOM/IN/00/LEM138 | 3 | cell-based format | Scientific Literature | |||
| 8. | ALA3586939 | T | Toxicity in po dosed rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA3586940 | A | Cytotoxicity against human skin fibroblast cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3586941 | F | Antileishmanial activity against Leishmania infantum MHOM/ES/2007/DP532JFJ infected in mouse BMDM cells assessed as reduction in infection at 150 uM after 48 hrs | Leishmania infantum | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3586942 | F | Antileishmanial activity against Leishmania donovani MHOM/IN/00/LEM138 infected in mouse BMDM cells assessed as reduction in infection at 150 uM after 48 hrs | Leishmania donovani | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA3586943 | F | Antileishmanial activity against Leishmania infantum promastigotes | Leishmania infantum | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3586944 | A | Cytotoxicity against mouse L929 cells assessed as survival rate at 25 to 250 uM after 72 hrs by trypan blue assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3586945 | A | Cytotoxicity against mouse L929 cells assessed as survival rate at 500 uM after 72 hrs by trypan blue assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3586946 | A | Cytotoxicity against mouse L929 cells assessed as survival rate at 1000 uM after 72 hrs by trypan blue assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3586947 | F | Antileishmanial activity against Leishmania infantum promastigotes infected in ICR (CD1) mouse assessed as parasite load in spleen at 200 mg/kg, po dosed daily starting 28 days after infection for 14 days by real-time PCR | Leishmania infantum | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA3586948 | F | Antileishmanial activity against Leishmania infantum promastigotes infected in ICR (CD1) mouse assessed as parasite load in liver at 200 mg/kg, po dosed daily starting 28 days after infection for 14 days by real-time PCR | Leishmania infantum | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3586951 | F | Antileishmanial activity against Leishmania infantum promastigotes infected in ICR (CD1) mouse assessed as reduction parasite load in spleen at 50 mg/kg, po dosed daily starting 28 days after infection for 14 days by real-time PCR relative to control | Leishmania infantum | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3586952 | F | Antileishmanial activity against Leishmania infantum promastigotes infected in ICR (CD1) mouse assessed as reduction parasite load in liver at 50 mg/kg, po dosed daily starting 28 days after infection for 14 days by real-time PCR relative to control | Leishmania infantum | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3586955 | T | Toxicity in ICR (CD1) mouse assessed as histological changes at 50 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature |
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