# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1032546 | F | Antiviral activity against HIV1 3B in human H9 cells assessed as inhibition of viral replication after 3 days by p24 antigen capture assay | Human immunodeficiency virus 1 | 17 | ALA1159288 | organism-based format | Scientific Literature | |
2. | ALA1032547 | A | Cytotoxicity against human H9 cells after 3 days | Homo sapiens | 17 | ALA1159288 | cell-based format | Scientific Literature | |
3. | ALA1032548 | A | Therapeutic index, ratio of IC50 for human H9 cells to EC50 for HIV1 3B | 15 | ALA1159288 | cell-based format | Scientific Literature | ||
4. | ALA2390555 | B | Binding affinity to HCV envelope protein E2 protein by SPR method | Hepatitis C virus | 1 | ALA2385072 | assay format | Scientific Literature | |
5. | ALA2390556 | B | Binding affinity to CD81 (unknown origin) | Homo sapiens | 1 | ALA2385072 | single protein format | Scientific Literature | |
6. | ALA2390557 | A | Cytotoxicity against human 293T cells at 50 uM after 48 hrs by Alamar Blue assay | Homo sapiens | 3 | ALA2385072 | cell-based format | Scientific Literature | |
7. | ALA2390558 | A | Cytotoxicity against human HeLa cells at 50 uM after 48 hrs by Alamar Blue assay | Homo sapiens | 3 | ALA2385072 | cell-based format | Scientific Literature | |
8. | ALA2390559 | A | Hemolytic activity against rabbit RBC after 60 mins by spectrophotometry | Oryctolagus cuniculus | 2 | ALA2385072 | cell-based format | Scientific Literature | |
9. | ALA2390560 | A | Cytotoxicity against human HepG2 cells at 50 uM after 48 hrs by Alamar Blue assay | Homo sapiens | 3 | ALA2385072 | cell-based format | Scientific Literature | |
10. | ALA2390561 | B | Inhibition of HCV envelope protein E2 protein interaction with CD81 receptor (unknown origin) by BIAcore assay | Hepatitis C virus | 1 | ALA2385072 | assay format | Scientific Literature | |
11. | ALA2390562 | B | Binding affinity to HCV envelope protein E2 protein by pull down assay | Hepatitis C virus | 1 | ALA2385072 | assay format | Scientific Literature | |
12. | ALA2390563 | F | Antiviral activity against pseudo HCV infected in human Huh7 cells at 10 uM after 72 hrs | Hepacivirus hominis | 1 | ALA2385072 | organism-based format | Scientific Literature | |
13. | ALA2390564 | F | Antiviral activity against pseudo HCV infected in human Huh7 cells assessed as inhibition of HCV pseudo particles entry at 10 uM incubated for 3 hrs prior to compound addition measured after 72 hrs | Hepacivirus hominis | 1 | ALA2385072 | organism-based format | Scientific Literature | |
14. | ALA2390565 | F | Antiviral activity against pseudo HCV infected in human Huh7 cells assessed as inhibition of HCV pseudo particles entry at 10 uM incubated for 3 hrs prior to virus addition measured after 72 hrs | Hepacivirus hominis | 1 | ALA2385072 | organism-based format | Scientific Literature | |
15. | ALA2390566 | F | Antiviral activity against pseudo HCV infected in human Huh7 cells assessed as inhibition of HCV pseudo particles entry at 10 uM incubated for 3 hrs | Hepacivirus hominis | 1 | ALA2385072 | organism-based format | Scientific Literature | |
16. | ALA2390567 | F | Antiviral activity against pseudo HCV infected in human Huh7 cells assessed as inhibition of HCV pseudo particles entry at 10 uM after 72 hrs | Hepacivirus hominis | 1 | ALA2385072 | organism-based format | Scientific Literature | |
17. | ALA2390568 | F | Antiviral activity against pseudo HCV infected in human 293T cells assessed as inhibition of HCV pseudo particles entry at 10 uM after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 26 | ALA2385072 | organism-based format | Scientific Literature | |
18. | ALA2390569 | F | Antiviral activity against pseudo HCV infected in human 293T cells assessed as inhibition of HCV pseudo particles entry after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 4 | ALA2385072 | organism-based format | Scientific Literature | |
19. | ALA2390570 | F | Antiviral activity against pseudo VSV infected in human 293T cells assessed as inhibition of vesicular stromatis G protein pseudo particles entry at 5 uM after 72 hrs by luciferase reporter gene assay | Vesicular stomatitis virus | 69 | ALA2385072 | organism-based format | Scientific Literature | |
20. | ALA2390571 | F | Antiviral activity against pseudo VSV infected in human 293T cells assessed as inhibition of vesicular stromatis G protein pseudo particles entry at 1 uM after 72 hrs by luciferase reporter gene assay | Vesicular stomatitis virus | 69 | ALA2385072 | organism-based format | Scientific Literature |