# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA949708 | Functional | Cytotoxicity against human HSC2 cells | Homo sapiens | 21 | ALA1150222 | cell-based format | Scientific Literature | |
2. | ALA949709 | ADME | Cytotoxicity against HGF cells | Homo sapiens | 21 | ALA1150222 | cell-based format | Scientific Literature | |
3. | ALA949710 | Unassigned | Selectivity ratio CC50 for HGF to CC50 for human HSC-2 cells | Homo sapiens | 17 | ALA1150222 | cell-based format | Scientific Literature | |
4. | ALA3405113 | Binding | Agonist activity at RARalpha (unknown origin) expressed in HEK293 cells assessed as transcriptional activation at 1 uM after 48 hrs by luciferase reporter gene assay | Homo sapiens | 5 | ALA3400029 | cell-based format | Scientific Literature | |
5. | ALA3405114 | Binding | Agonist activity at RARalpha (unknown origin) expressed in HEK293 cells assessed as transcriptional activation after 48 hrs by luciferase reporter gene assay | Homo sapiens | 4 | ALA3400029 | cell-based format | Scientific Literature | |
6. | ALA3405115 | Binding | Agonist activity at RARalpha (unknown origin) expressed in HEK293 cells assessed as transcriptional activation after 48 hrs by luciferase reporter gene assay in presence of bexarotene | Homo sapiens | 4 | ALA3400029 | cell-based format | Scientific Literature | |
7. | ALA4056679 | Binding | Agonist activity at AhR in human HepG2 cells at 1 to 10 uM after 42 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 4 | ALA4052721 | cell-based format | Scientific Literature | |
8. | ALA4056682 | Binding | Agonist activity at AhR in human HepG2 cells after 42 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4052721 | cell-based format | Scientific Literature | |
9. | ALA4056683 | ADME | Cytotoxicity against human HepG2 cells at 20 uM | Homo sapiens | 1 | ALA4052721 | cell-based format | Scientific Literature | |
10. | ALA4056684 | Binding | Agonist activity at AhR in human HepG2 cells at 2.5 to 10 uM after 42 hrs in presence of AhR antagonist GNF-351 by luciferase reporter gene assay | Homo sapiens | 1 | ALA4052721 | cell-based format | Scientific Literature | |
11. | ALA4056685 | Binding | Agonist activity at AhR in human HepG2 cells at 2.5 to 10 uM after 42 hrs in presence of AhR antagonist 3',4'-DMF by luciferase reporter gene assay | Homo sapiens | 1 | ALA4052721 | cell-based format | Scientific Literature | |
12. | ALA4056686 | Binding | Agonist activity at AhR in human HepG2 cells at 2.5 to 10 uM after 42 hrs in presence of AhR antagonist CH-223191 by luciferase reporter gene assay | Homo sapiens | 1 | ALA4052721 | cell-based format | Scientific Literature | |
13. | ALA4056689 | ADME | Agonist activity at AhR in human HepG2 cells assessed as increase in CYP1A1 mRNA level at 10 uM after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA4052721 | cell-based format | Scientific Literature | |
14. | ALA4056690 | ADME | Agonist activity at AhR in human HepG2 cells assessed as increase in CYP1A1 expression at 10 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4052721 | cell-based format | Scientific Literature | |
15. | ALA4056691 | Binding | Agonist activity at AhR in human HuH7 cells assessed as reduction in IL-1beta induced increase in SAA1 mRNA level at 10 uM pretreated for 20 hrs followed by Il-1beta addition measured after 4 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA4052721 | cell-based format | Scientific Literature | |
16. | ALA5224156 | Functional | Antibacterial activity against Bacillus subtilis PCI 219 incubated for 20 hrs by Mueller-Hinton broth based agar based dilution method | Bacillus subtilis | 2 | ALA5223092 | organism-based format | Scientific Literature | |
17. | ALA5224158 | Functional | Antibacterial activity against methicillin resistant Staphylococcus aureus incubated for 20 hrs by Mueller-Hinton broth based agar based dilution method | Staphylococcus aureus | 2 | ALA5223092 | organism-based format | Scientific Literature | |
18. | ALA5224159 | Functional | Antibacterial activity against Micrococcus luteus ATCC 9341 incubated for 20 hrs by Mueller-Hinton broth based agar based dilution method | Micrococcus luteus | 2 | ALA5223092 | organism-based format | Scientific Literature |