# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1004867 | Functional | Effect on neutrophil elastase protein expression in human U937 cells at 30 uM after 7 days by Western blot | Homo sapiens | 1 | ALA1156470 | cell-based format | Scientific Literature | |
2. | ALA1004868 | Binding | Inhibition of human recombinant cathepsin C after 10 mins | Homo sapiens | 12 | ALA1156470 | single protein format | Scientific Literature | |
3. | ALA1004869 | Binding | Inhibition of human recombinant cathepsin B after 10 mins | Homo sapiens | 12 | ALA1156470 | single protein format | Scientific Literature | |
4. | ALA1004870 | Binding | Inhibition of human recombinant cathepsin S after 10 mins | Homo sapiens | 12 | ALA1156470 | single protein format | Scientific Literature | |
5. | ALA1004871 | Binding | Inhibition of human recombinant cathepsin L after 10 mins | Homo sapiens | 12 | ALA1156470 | single protein format | Scientific Literature | |
6. | ALA1004872 | Binding | Inhibition of human recombinant cathepsin H after 10 mins | Homo sapiens | 12 | ALA1156470 | single protein format | Scientific Literature | |
7. | ALA1004874 | Binding | Inhibition of cathepsin C in human U937 cells at 30 uM after 24 hrs | Homo sapiens | 2 | ALA1156470 | cell-based format | Scientific Literature | |
8. | ALA1004876 | Functional | Cytotoxicity against human U937 cells at 30 uM after 72 hrs annexin-V propidium iodide method | Homo sapiens | 2 | ALA1156470 | cell-based format | Scientific Literature | |
9. | ALA1004877 | Binding | Inhibition of neutrophil elastase in human U937 cells | Homo sapiens | 3 | ALA1156470 | cell-based format | Scientific Literature | |
10. | ALA1004878 | Binding | Inhibition of cathepsin G in human U937 cells | Homo sapiens | 3 | ALA1156470 | cell-based format | Scientific Literature | |
11. | ALA1004879 | Binding | Inhibition of proteinase-3 in human U937 cells | Homo sapiens | 2 | ALA1156470 | cell-based format | Scientific Literature | |
12. | ALA1004880 | Binding | Inhibition of intracellular cathepsin C active site in human U937 cells assessed as reduction of Ala-4[125I]Phe-DMK labeled 23 kDa protein at 10 uM by autoradiography based pulse chase assay | Homo sapiens | 1 | ALA1156470 | cell-based format | Scientific Literature | |
13. | ALA1007393 | Binding | Inhibition of intracellular cathepsin C active site in human U937 cells assessed as reduction of Ala-4[125I]Phe-DMK labeled 27 kDa protein at 10 uM by autoradiography based pulse chase assay | Homo sapiens | 1 | ALA1156470 | cell-based format | Scientific Literature | |
14. | ALA1007394 | Binding | Inhibition of intracellular cathepsin C active site in human U937 cells assessed as reduction of Ala-4[125I]Phe-DMK labeled 43 kDa protein at 10 uM by autoradiography based pulse chase assay | Homo sapiens | 1 | ALA1156470 | cell-based format | Scientific Literature | |
15. | ALA1007397 | Binding | Blockade of cathepsin G processing in human U937 cells by densitometry | Homo sapiens | 7 | ALA1156470 | cell-based format | Scientific Literature | |
16. | ALA1007398 | Binding | Blockade of neutrophil elastase processing in human U937 cells after 7 days by fluorogenic substrate cleavage assay | Homo sapiens | 6 | ALA1156470 | cell-based format | Scientific Literature | |
17. | ALA1007399 | Binding | Inhibition of neutrophil elastase activation in human U937 cells at 1 uM | Homo sapiens | 1 | ALA1156470 | cell-based format | Scientific Literature | |
18. | ALA1007400 | Binding | Inhibition of neutrophil elastase activity in beta-estradiol differentiated mouse EcoM-G cells at 10 uM after 24 hrs in the absence of estradiol | Mus musculus | 1 | ALA1156470 | cell-based format | Scientific Literature | |
19. | ALA1007401 | Binding | Inhibition of cathepsin G activity in beta-estradiol differentiated mouse EcoM-G cells at 10 uM after 24 hrs in the absence of estradiol | Mus musculus | 1 | ALA1156470 | cell-based format | Scientific Literature | |
20. | ALA1007402 | Binding | Inhibition of proteinase-3 activity in beta-estradiol differentiated mouse EcoM-G cells at 10 uM after 24 hrs in the absence of estradiol | Mus musculus | 1 | ALA1156470 | cell-based format | Scientific Literature |