# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA964480 | B | Binding affinity to calf thymus DNA assessed as melting temperature at 1 uM by fluorescence titration | Bos taurus | 6 | nucleic acid format | Scientific Literature | ||
2. | ALA964482 | B | Binding affinity to calf thymus DNA by fluorescence titration | Bos taurus | 6 | nucleic acid format | Scientific Literature | ||
3. | ALA964484 | B | Inhibition of human topoisomerase 1 mediated pLAZ DNA relaxation by gel electrophoresis | Homo sapiens | 8 | assay format | Scientific Literature | ||
4. | ALA964486 | F | Cytotoxicity against human mitoxantrone-sensitive HL60 cells after 72 hrs | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
5. | ALA964487 | F | Cytotoxicity against mitoxantrone-resistant human HL60/MX2 cells after 72 hrs | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
6. | ALA965236 | F | Resistant index, ratio of IC50 for mitoxantrone-resistant human HL60/MX2 cells to IC50 for mitoxantrone-sensitive human HL60 cells | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
7. | ALA954855 | B | Inhibition of human topoisomerase 2 mediated pLAZ DNA relaxation by gel electrophoresis | Homo sapiens | 8 | assay format | Scientific Literature | ||
8. | ALA4303805 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
9. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | assay format | SARS-CoV-2 Screening Data 2020-21 | ||
10. | ALA4495583 | F | SARS-CoV-2 3CL-Pro protease inhibition IC50 determined by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 109 | assay format | SARS-CoV-2 Screening Data 2020-21 | ||
11. | ALA4495584 | F | MERS_3CL Pro protease inhibition IC50 by FRET kind of response from peptide substrate | Middle East respiratory syndrome-related coronavirus | 80 | assay format | SARS-CoV-2 Screening Data 2020-21 | ||
12. | ALA4495585 | F | MERS 3CL-Pro protease inhibition percentage at 10 µM by FRET kind of response from peptide substrate | Middle East respiratory syndrome-related coronavirus | 70 | assay format | SARS-CoV-2 Screening Data 2020-21 | ||
13. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
14. | ALA4808149 | B | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | single protein format | Fraunhofer HDAC6 | ||
15. | ALA4808150 | B | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | single protein format | Fraunhofer HDAC6 | ||
16. | ALA5241850 | B | Inhibition of topoisomerase 1 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
17. | ALA5241851 | B | Inhibition of topoisomerase 2 (unknown origin) | Homo sapiens | 2 | assay format | Scientific Literature | ||
18. | ALA5241852 | F | Antiproliferative activity against mouse P338 cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
19. | ALA5241853 | F | Antiproliferative activity against human KB cells | Homo sapiens | 1 | cell-based format | Scientific Literature |