# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA958065 | F | Agonist activity at human P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation at 10 uM by scintillation proximity assay | Homo sapiens | 10 | ALA1150771 | cell-based format | Scientific Literature | |
2. | ALA958066 | F | Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity assay | Homo sapiens | 35 | ALA1150771 | cell-based format | Scientific Literature | |
3. | ALA958068 | F | Agonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate accumulation by scintillation proximity assay | Homo sapiens | 32 | ALA1150771 | cell-based format | Scientific Literature | |
4. | ALA4046665 | B | Inhibition of wild-type HCV genotype 1b NS5B RNA dependent RNA polymerase | Hepatitis C virus subtype 1b | 3 | ALA4043192 | assay format | Scientific Literature | |
5. | ALA4046666 | B | Inhibition of HCV genotype 1b NS5B RNA dependent RNA polymerase S282T mutant | Hepatitis C virus subtype 1b | 3 | ALA4043192 | assay format | Scientific Literature | |
6. | ALA4046667 | B | Selectivity ratio of IC50 for HCV genotype 1b NS5B RNA dependent RNA polymerase S282T mutant to IC50 for wild-type HCV genotype 1b NS5B RNA dependent RNA polymerase | Hepatitis C virus subtype 1b | 3 | ALA4043192 | assay format | Scientific Literature | |
7. | ALA4123982 | B | Inhibition of Dengue virus RdRp activity using 5'-(TCAG)20(TCCAAG)14(TCAG)20-3' as template measured after 120 mins | Dengue virus | 9 | ALA4118212 | single protein format | Scientific Literature | |
8. | ALA4123983 | A | Inhibition of human POLRMT using 5'-FAM labelled RNA primer/DNA template duplex assessed as single nucleotide incorporation rate at 500 uM after 5 mins by SDS-PAGE analysis relative to control | Homo sapiens | 9 | ALA4118212 | single protein format | Scientific Literature | |
9. | ALA4394394 | A | Inhibition of human DNA polymerase-alpha assessed as reduction in [3H]dTTP incorporation in to activated calf thymus DNA substrate at 100 uM by scintillation counting method relative to control | Homo sapiens | 8 | ALA4393666 | single protein format | Scientific Literature | |
10. | ALA4394396 | A | Inhibition of human DNA polymerase-beta assessed as reduction in [3H]dTTP incorporation in to activated calf thymus DNA substrate at 100 uM by scintillation counting method relative to control | Homo sapiens | 8 | ALA4393666 | single protein format | Scientific Literature | |
11. | ALA4394397 | A | Inhibition of human DNA polymerase-gamma assessed as reduction in [3H]dTTP incorporation in to activated calf thymus DNA substrate at 100 uM by scintillation counting method relative to control | Homo sapiens | 8 | ALA4393666 | single protein format | Scientific Literature | |
12. | ALA4394398 | A | Inhibition of RNA polymerase 2 in human HeLa cell nuclear extract assessed as reduction in RNA transcription by PAGE analysis | Homo sapiens | 8 | ALA4393666 | cell-based format | Scientific Literature | |
13. | ALA4394399 | A | Inhibition of human mitochondrial DNA-dependent RNA polymerase activity at 100 uM using 33P-RNA/DNA primer/template by phosphor-imaging analysis | Homo sapiens | 4 | ALA4393666 | single protein format | Scientific Literature | |
14. | ALA4413708 | A | Substrate activity at human POLRMT assessed as 5-radiolabled RNA/DNA incorporation levels at 100 uM after 2 hrs by PAGE analysis | Homo sapiens | 3 | ALA4411318 | single protein format | Scientific Literature | |
15. | ALA4413722 | B | Inhibition of NS5B polymerase in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysis | Hepatitis C virus subtype 1b | 2 | ALA4411318 | cell-based format | Scientific Literature | |
16. | ALA4413723 | B | Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysis | Hepatitis C virus subtype 1a | 2 | ALA4411318 | cell-based format | Scientific Literature | |
17. | ALA4413724 | B | Inhibition of NS5B polymerase in HCV genotype 3a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysis | Hepatitis C virus subtype 3a | 2 | ALA4411318 | cell-based format | Scientific Literature | |
18. | ALA4413725 | B | Inhibition of NS5B polymerase in HCV genotype 6a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysis | Hepatitis C virus subtype 6a | 2 | ALA4411318 | cell-based format | Scientific Literature | |
19. | ALA4413726 | B | Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysis | Hepatitis C virus subtype 1b | 2 | ALA4411318 | cell-based format | Scientific Literature | |
20. | ALA4413727 | B | Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 96 hrs by RT-PCR analysis | Hepatitis C virus subtype 2a | 2 | ALA4411318 | cell-based format | Scientific Literature |