# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA661070 | F | Dose estimated to produce 25 mm Hg fall in mean systemic blood pressure of anesthetized cat at 10 min after administration | Felis catus | 45 | ALA1122780 | organism-based format | Scientific Literature | |
2. | ALA740243 | T | Acute toxicity was measured as LD50 in mice after ip administration. | Mus musculus | 3 | ALA1121897 | organism-based format | Scientific Literature | |
3. | ALA771214 | F | Area under curve was determined for 0-6 hr duration using dihydralazine as reference drug for the peak blood pressure | Rattus norvegicus | 1 | ALA1123264 | organism-based format | Scientific Literature | |
4. | ALA776113 | F | Antihypertensive activity was measured as ED20 which is the dose lowered the normal arterial pressure in conscious SH rats by 20% after po administration. | Rattus norvegicus | 3 | ALA1121897 | organism-based format | Scientific Literature | |
5. | ALA781586 | F | Hypotensive activity was measured as ED20 which is the dose lowered the normal arterial pressure in anesthetized rats by 20% after ip administration. | Rattus norvegicus | 2 | ALA1121897 | organism-based format | Scientific Literature | |
6. | ALA781588 | F | Hypotensive activity was measured as ED20 which is the dose lowered the normal arterial pressure in anesthetized rats by 20% after iv administration. | Rattus norvegicus | 5 | ALA1121897 | organism-based format | Scientific Literature | |
7. | ALA780852 | F | Compound was tested for antihypertensive activity in normotensive rats and the dose that lowered by 25 mmHg of the blood pressure was determined | Rattus norvegicus | 1 | ALA1123264 | organism-based format | Scientific Literature | |
8. | ALA780859 | F | Dose that lowers blood pressure by 25 mm Hg was determined in spontaneous hypertensive rats (SHR) | Rattus norvegicus | 6 | ALA1123264 | organism-based format | Scientific Literature | |
9. | ALA778158 | F | Difference in systolic blood pressure of SH rats observed prior to the first application and 2 hr after the fifth application at the oral dose of 5 mg/kg was expressed as Delta BP | Rattus norvegicus | 10 | ALA1122780 | organism-based format | Scientific Literature | |
10. | ALA784532 | F | divya_inp96 Antihypertensive activity in hypertensive rats, after peroral administration that lowered the blood pressure by 50 mmHg | Rattus norvegicus | 1 | ALA1124348 | organism-based format | Scientific Literature | |
11. | ALA790536 | F | Relative potency of compound was measured in anesthetized rats after iv administration. | Rattus norvegicus | 5 | ALA1121897 | organism-based format | Scientific Literature | |
12. | ALA790538 | F | Relative potency of compound was measured in conscious SH rats after po administration. | Rattus norvegicus | 4 | ALA1121897 | organism-based format | Scientific Literature | |
13. | ALA791675 | F | Antihypertensive action versus dihydralazine | Rattus norvegicus | 6 | ALA1124348 | organism-based format | Scientific Literature | |
14. | ALA790289 | F | Variation in heart rate when 25 mg/kg administered orally in rats | Rattus norvegicus | 8 | ALA1124348 | organism-based format | Scientific Literature | |
15. | ALA840551 | F | In vitro inhibition of ADP-induced human platelet aggregation | Homo sapiens | 41 | ALA1122226 | organism-based format | Scientific Literature | |
16. | ALA840552 | F | In vitro inhibition of collagen-induced human platelet aggregation. | Homo sapiens | 43 | ALA1122226 | organism-based format | Scientific Literature | |
17. | ALA841426 | F | Relative activity (compared to acetylsalicylic acid) for in vitro inhibition of collagen-induced human platelet aggregation | Homo sapiens | 43 | ALA1122226 | organism-based format | Scientific Literature | |
18. | ALA844698 | F | relative activity with respect to the dihydralazine was determined | 1 | ALA1123264 | assay format | Scientific Literature | ||
19. | ALA847714 | F | In vitro hypotensive activity in anesthetized rats after intraperitoneal administration. | Rattus norvegicus | 41 | ALA1122226 | organism-based format | Scientific Literature | |
20. | ALA849664 | F | Activity relative to dihydralazine for in vitro hypotensive activity in anesthetized rats | Rattus norvegicus | 41 | ALA1122226 | organism-based format | Scientific Literature |