# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA651328 | B | Tested for the inhibition of [14C]-DDATHF influx in CCRF-CEM cells of human leukemic lymphoblast | 1 | ALA1127804 | cell-based format | Scientific Literature | ||
2. | ALA659476 | F | Tested for inhibition of [14C]-DDATHF influx in CEM/MTX cells of human leukemic lymphoblasts | Homo sapiens | 4 | ALA1127804 | cell-based format | Scientific Literature | |
3. | ALA743892 | F | Effect on Pneumocystis carinii pneumonia in SCID mice | Mus musculus | 1 | ALA1129493 | organism-based format | Scientific Literature | |
4. | ALA744870 | F | Number of mice infected to tat of total number of mice (11/11) | Mus musculus | 1 | ALA1129493 | organism-based format | Scientific Literature | |
5. | ALA850372 | F | Ratio between Ki values of CCRF-CEM and CEM/MTX | 4 | ALA1127804 | cell-based format | Scientific Literature | ||
6. | ALA916845 | F | Protection against methotrexate-induced effect in human CCRF-CEM cells assessed as growth inhibition at 0.1 mM | Homo sapiens | 1 | ALA1149301 | cell-based format | Scientific Literature | |
7. | ALA916849 | F | Protection against methotrexate-induced effect in human CCRF-CEM cells assessed as growth inhibition at 10 mM | Homo sapiens | 1 | ALA1149301 | cell-based format | Scientific Literature | |
8. | ALA1006403 | B | Inhibition of human RFC-mediated [3H]MTX transport in Chinese hamster PC43-10 cells at 10 uM | Homo sapiens | 4 | ALA1156629 | cell-based format | Scientific Literature | |
9. | ALA1006005 | B | Effect on human MRP2-mediated estradiol-17-beta-glucuronide transport in Sf9 cells inverted membrane vesicles relative to control | Homo sapiens | 189 | ALA1150338 | cell-based format | Scientific Literature | |
10. | ALA1035433 | A | Total body clearance in human | Homo sapiens | 390 | ALA1151930 | organism-based format | Scientific Literature | |
11. | ALA1035434 | A | Renal clearance in human | Homo sapiens | 390 | ALA1151930 | organism-based format | Scientific Literature | |
12. | ALA1043580 | A | Fraction unbound in human plasma | Homo sapiens | 276 | ALA1156824 | cell-free format | Scientific Literature | |
13. | ALA1043581 | A | Total clearance in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
14. | ALA1043582 | A | Hepatic clearance in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
15. | ALA1043583 | A | Renal clearance in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
16. | ALA1043584 | A | Oral bioavailability in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
17. | ALA1043585 | A | Fraction absorbed in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
18. | ALA1043586 | A | Fraction escaping gut-wall elimination in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
19. | ALA1043587 | A | Fraction escaping hepatic elimination in human | Homo sapiens | 308 | ALA1156824 | organism-based format | Scientific Literature | |
20. | ALA1043588 | A | Volume of distribution at steady state in human | Homo sapiens | 300 | ALA1156824 | organism-based format | Scientific Literature |