# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA701775 | Functional | Concentration required to reduce growth of human jurkat leukemia cells to 50% of control cultures, determined using a 72 hr continuous exposure | Homo sapiens | 42 | ALA1127825 | cell-based format | Scientific Literature | |
2. | ALA703726 | Functional | Drug concentration in mole/kg/day providing 50% extension of life in intraperitoneally implanted leukemia L1210 mice. | Mus musculus | 771 | ALA1122023 | cell-based format | Scientific Literature | |
3. | ALA838923 | ADME | In vitro therapeutic index value is the ratio between IC50 values of [J] and [P] | 41 | ALA1127825 | cell-based format | Scientific Literature | ||
4. | ALA1217000 | Functional | Antimicrobial activity against Plasmodium falciparum | Plasmodium falciparum | 630 | ALA1212812 | organism-based format | Scientific Literature | |
5. | ALA762989 | Functional | Inhibitory concentration IC50 against Plasmodium falciparum K1 by [3H]hypoxanthine uptake over 24 hr | Plasmodium falciparum | 42 | ALA1127825 | organism-based format | Scientific Literature | |
6. | ALA813896 | ADME | Compound concentration in mole/kg/day lethal to 10% of mice | Mus sp. | 771 | ALA1122023 | organism-based format | Scientific Literature | |
7. | ALA813449 | Binding | Minimum inhibitory concentration required to completely inhibit topoisomerase II activity from Plasmodium falciparum was determined using P4 DNA decatenation assay | Plasmodium falciparum K1 | 12 | ALA1127825 | single protein format | Scientific Literature | |
8. | ALA856990 | Binding | Minimum inhibitory concentration required to completely inhibit topoisomerase II activity from jurkat human leukemia cells was determined using P4 DNA unknotting assay | 12 | ALA1127825 | assay format | Scientific Literature | ||
9. | ALA1016906 | Functional | Antimalarial activity against chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 after 24 hrs by [3H]hypoxanthine uptake | Plasmodium falciparum | 12 | ALA1154474 | organism-based format | Scientific Literature |