# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1008159 | ADME | Inhibition of CYP3A4 in human HepG2/C3A cells assessed as testosterone-6-hydroxylase activity | Homo sapiens | 3 | ALA1155958 | cell-based format | Scientific Literature | |
2. | ALA1008160 | ADME | Inhibition of human recombinant CYP3A4 expressed in insect cell microsome assessed as testosterone-6-hydroxylase activity at 4 uM after 60 mins | Homo sapiens | 1 | ALA1155958 | microsome format | Scientific Literature | |
3. | ALA997007 | Binding | Inhibition of CYP4F2-mediated gamma-tocopherol metabolism in human HepG2/C3A cells preincubated for 4 hrs and continued for 48 hrs | Homo sapiens | 4 | ALA1155958 | cell-based format | Scientific Literature | |
4. | ALA997008 | Binding | Inhibition of CYP4F2-mediated gamma-tocopherol metabolism in human HepG2/C3A cells at 1 uM preincubated for 6 hrs and continued for 24 hrs | Homo sapiens | 1 | ALA1155958 | cell-based format | Scientific Literature | |
5. | ALA997009 | Functional | Effect on total cell protein level in human HepG2/C3A cells | Homo sapiens | 1 | ALA1155958 | cell-based format | Scientific Literature | |
6. | ALA997010 | Functional | Effect on cell morphology in human HepG2/C3A cells | Homo sapiens | 1 | ALA1155958 | cell-based format | Scientific Literature | |
7. | ALA997013 | Functional | Enrichment in delta-tocopherol in FVB/N mouse liver assessed as doubling in delta-tocopherol/alpha-tocopherol ratio at 500 mg/kg in delta-tocopherol rich diet for 10 days | Mus musculus | 1 | ALA1155958 | organism-based format | Scientific Literature | |
8. | ALA997014 | Functional | Enrichment in delta-tocopherol in FVB/N mouse bile assessed as tripling in delta-tocopherol/alpha-tocopherol ratio at 500 mg/kg in delta-tocopherol rich diet for 10 days | Mus musculus | 1 | ALA1155958 | organism-based format | Scientific Literature |