# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1005552 | B | Inhibition of human recombinant indoleamine 2,3-dioxygenase in presence of L-tryptophan substrate | Homo sapiens | 31 | ALA1156570 | single protein format | Scientific Literature | |
2. | ALA1005553 | B | Inhibition of human recombinant indoleamine 2,3-dioxygenase by Eadie-Hofstee plot | Homo sapiens | 4 | ALA1156570 | single protein format | Scientific Literature | |
3. | ALA3630804 | B | Inhibition of IDO1 (unknown origin) | Homo sapiens | 11 | ALA3627665 | single protein format | Scientific Literature | |
4. | ALA4007862 | B | Inhibition of recombinant human IDO1 expressed in bacterial expression system using L-Tryptophan as substrate after 25 mins in absence of GSH and presence of tween20 by fluorescence assay | Homo sapiens | 57 | ALA4007389 | assay format | Scientific Literature | |
5. | ALA4007866 | B | Inhibition of recombinant human IDO1 S167A mutant expressed in Escherichia coli SG13009(pREP4) using L-Tryptophan as substrate after 25 mins by fluorescence assay | Homo sapiens | 66 | ALA4007389 | assay format | Scientific Literature | |
6. | ALA4007867 | B | Selectivity ratio of IC50 for recombinant human IDO1 S167A mutant expressed in Escherichia coli SG13009(pREP4) to IC50 for recombinant human IDO1 expressed in bacterial expression system | Homo sapiens | 47 | ALA4007389 | assay format | Scientific Literature | |
7. | ALA4007890 | B | Inhibition of full length recombinant human His-tagged IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrs | Homo sapiens | 58 | ALA4007389 | cell-based format | Scientific Literature | |
8. | ALA4007891 | A | Cytotoxicity against mouse LLTC cells assessed as reduction in cell viability after 24 hrs by MTT assay | Mus musculus | 60 | ALA4007389 | cell-based format | Scientific Literature | |
9. | ALA4355075 | B | Inhibition of recombinant human IDO1 assessed as reduction in N-formyl-kynurenine level using L-tryptophan as substrate incubated for 60 mins | Homo sapiens | 1 | ALA4354789 | single protein format | Scientific Literature | |
10. | ALA4367261 | B | Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins by spectrophotometric method | Homo sapiens | 87 | ALA4364294 | single protein format | Scientific Literature | |
11. | ALA4367262 | B | Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrs | Homo sapiens | 73 | ALA4364294 | cell-based format | Scientific Literature | |
12. | ALA4834557 | B | Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 20 mins by HPLC analysis | Homo sapiens | 53 | ALA4834395 | cell-based format | Scientific Literature | |
13. | ALA4834559 | A | Cytotoxicity against human HEK293T cells assessed as reduction in cell viability at 200 uM after 7 hrs by DAPI staining based assay | Homo sapiens | 36 | ALA4834395 | cell-based format | Scientific Literature |