# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA971698 | B | Inhibition of CDK2/Cyclin A by radiometric assay | 29 | ALA1156543 | single protein format | Scientific Literature | ||
2. | ALA971700 | B | Inhibition of CDK1/Cyclin B by radiometric assay | 7 | ALA1156543 | protein complex format | Scientific Literature | ||
3. | ALA971707 | F | Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by alamar blue assay | Homo sapiens | 15 | ALA1156543 | cell-based format | Scientific Literature | |
4. | ALA971708 | A | Plasma clearance in BALB/c mouse bearing human HCT116 cells xenografts at 0.2 mg/kg, iv | Mus musculus | 11 | ALA1156543 | organism-based format | Scientific Literature | |
5. | ALA3607094 | B | Inhibition of CDK2/cyclin A (unknown origin) by radiometric filter binding assay | Homo sapiens | 6 | ALA3603804 | protein complex format | Scientific Literature | |
6. | ALA3607098 | F | Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by Alamar blue assay | Homo sapiens | 3 | ALA3603804 | cell-based format | Scientific Literature | |
7. | ALA4151772 | F | Protection against cisplatin-induced cell death in neonatal mouse HEI-OC1 cells assessed as reduction in caspase-3/7 activity | Mus musculus | 53 | ALA4145685 | assay format | Scientific Literature | |
8. | ALA4151776 | B | Inhibition of C-terminal His6-tagged human full length CDK2/N-terminal GST-tagged human full length Cyclin A using histone H1 and [gamma-32P]-ATP incubated for 30 mins by phosphorimage based assay | Homo sapiens | 19 | ALA4145685 | protein complex format | Scientific Literature | |
9. | ALA4151777 | F | Protection against cisplatin-induced toxicity in P3 mouse cochlear explants assessed as increase in outer hair cell count at 150 nM incubated for 24 hrs by phalloidin staining based confocal microscopy | Mus musculus | 4 | ALA4145685 | tissue-based format | Scientific Literature | |
10. | ALA4613393 | B | Inhibition of full length GST-tagged human CDK2/Cyclin A | Homo sapiens | 1 | ALA4613207 | protein complex format | Scientific Literature | |
11. | ALA4613395 | B | Inhibition of full length GST-tagged human CDK1/cyclin B | Homo sapiens | 1 | ALA4613207 | protein complex format | Scientific Literature | |
12. | ALA4684781 | F | Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth at 8 uM measured after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 38 | ALA4680185 | cell-based format | Scientific Literature | |
13. | ALA4684782 | F | Antiproliferative activity against human H460 cells assessed as inhibition of cell growth at 8 uM measured after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 38 | ALA4680185 | cell-based format | Scientific Literature | |
14. | ALA4684784 | B | Inhibition of recombinant human full length CDK2/cyclin A2 at 10 uM incubated for 10 mins by ADP-Glo reagent assay relative to control | Homo sapiens | 36 | ALA4680185 | protein complex format | Scientific Literature | |
15. | ALA4684785 | F | Antiproliferative activity against human HCT116 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | ALA4680185 | cell-based format | Scientific Literature | |
16. | ALA4684786 | F | Antiproliferative activity against human H460 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | ALA4680185 | cell-based format | Scientific Literature | |
17. | ALA4684787 | F | Antiproliferative activity against human A375 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | ALA4680185 | cell-based format | Scientific Literature | |
18. | ALA4684788 | F | Antiproliferative activity against human Hela cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | ALA4680185 | cell-based format | Scientific Literature | |
19. | ALA4684789 | F | Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 17 | ALA4680185 | cell-based format | Scientific Literature | |
20. | ALA4684790 | A | Cytotoxicity against mouse NIH/3T3 cells incubated for 72 hrs by CCK-8 assay | Mus musculus | 4 | ALA4680185 | cell-based format | Scientific Literature |