# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA989886 | Binding | Activation of AMPKalpha in rat L6 cells assessed as ATP concentration per mg of protein at 5 uM in presence of 23 mM D-glucose | Rattus norvegicus | 1 | ALA1151715 | cell-based format | Scientific Literature | |
2. | ALA989890 | Functional | Effect on [3H]2-deoxy-D-glucose uptake in rat L6 cells at 150 uM relative to control | Rattus norvegicus | 3 | ALA1151715 | cell-based format | Scientific Literature | |
3. | ALA989891 | Functional | Effect on [3H]2-deoxy-D-glucose uptake in rat L6 cells at 50 uM relative to control | Rattus norvegicus | 3 | ALA1151715 | cell-based format | Scientific Literature | |
4. | ALA989894 | ADME | Fraction unbound in fetal calf serum at 5 uM | Bos taurus | 1 | ALA1151715 | cell-free format | Scientific Literature | |
5. | ALA989895 | Functional | Increase in GLUT1myc abundance in rat L6 cell membrane at 20 mM after 7 hrs | Rattus norvegicus | 4 | ALA1151715 | cell-based format | Scientific Literature | |
6. | ALA989896 | Functional | Increase in GLUT1myc abundance in rat L6 cell membrane at 5 UM after 18 hrs | Rattus norvegicus | 4 | ALA1151715 | cell-based format | Scientific Literature | |
7. | ALA990678 | Functional | Increase in GLUT1myc abundance in rat L6 cell membrane at 150 uM after 7 hrs | Rattus norvegicus | 4 | ALA1151715 | cell-based format | Scientific Literature | |
8. | ALA989818 | Functional | Increase in GLUT1myc abundance in rat L6 cell membrane at 50 uM after 7 hrs | Rattus norvegicus | 4 | ALA1151715 | cell-based format | Scientific Literature | |
9. | ALA989820 | Binding | Activation of 5-AMP-induced AMPKalpha in rat L6 cells assessed as reduction in Tyr172 phosphorylation at 5 uM relative to control in presence of compound C | Rattus norvegicus | 1 | ALA1151715 | cell-based format | Scientific Literature | |
10. | ALA988981 | Functional | Effect on [3H]2-deoxy-D-glucose uptake in rat L6 cells at 200 uM relative to control | Rattus norvegicus | 2 | ALA1151715 | cell-based format | Scientific Literature | |
11. | ALA988991 | ADME | Cytotoxicity against rat L6 cells by MTT assay | Rattus norvegicus | 21 | ALA1151715 | cell-based format | Scientific Literature | |
12. | ALA988992 | Functional | Effect on [3H]2-deoxy-D-glucose uptake in rat L6 cells at 5 uM relative to control | Rattus norvegicus | 3 | ALA1151715 | cell-based format | Scientific Literature | |
13. | ALA988995 | Functional | Effect on [3H]2-deoxy-D-glucose uptake in human skeletal muscle cells at 5 uM relative to control | Homo sapiens | 1 | ALA1151715 | assay format | Scientific Literature | |
14. | ALA988999 | Functional | Increase in GLUT4myc abundance in rat L6 cell membrane at 5 UM after 18 hrs | Rattus norvegicus | 1 | ALA1151715 | cell-based format | Scientific Literature | |
15. | ALA989003 | Functional | Inhibition of [3H]2-deoxy-D-glucose uptake in rat L6 cells at 5 uM in presence of 100 nM wortmannin | Rattus norvegicus | 1 | ALA1151715 | cell-based format | Scientific Literature | |
16. | ALA989007 | Binding | Activation of 5-AMP-induced AMPKalpha in rat L6 cells assessed as Tyr172 phosphorylation at 5 uM relative to control | Rattus norvegicus | 1 | ALA1151715 | cell-based format | Scientific Literature | |
17. | ALA991712 | Binding | Activation of 5-AMP-induced AMPKalpha in human skeletal muscle cells assessed as Tyr172 phosphorylation at 5 uM relative to control | Homo sapiens | 1 | ALA1151715 | assay format | Scientific Literature |