# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA989834 | B | Inhibition of human CYP11B2 expressed in hamster V79 MZh cells at 500 nM | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
2. | ALA989835 | B | Inhibition of human CYP11B2 expressed in hamster V79 MZh cells | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
3. | ALA989836 | B | Inhibition of human CYP11B1 expressed in hamster V79 MZh cells | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
4. | ALA989837 | B | Selectivity ratio, IC50 for human CYP11B1 to IC50 for human CYP11B2 | Homo sapiens | 27 | assay format | Scientific Literature | ||
5. | ALA989838 | F | Inhibition of human CYP17 expressed in Escherichia coli at 2.5 uM | Homo sapiens | 20 | assay format | Scientific Literature | ||
6. | ALA989839 | F | Inhibition of human placental CYP19 at 500 nM | Homo sapiens | 17 | assay format | Scientific Literature | ||
7. | ALA989840 | A | Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomes at 2 uM | Homo sapiens | 20 | microsome format | Scientific Literature | ||
8. | ALA989843 | A | Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomes | Homo sapiens | 21 | microsome format | Scientific Literature | ||
9. | ALA989844 | A | Inhibition of human recombinant CYP2B6 expressed in baculovirus-infected insect microsomes | Homo sapiens | 8 | microsome format | Scientific Literature | ||
10. | ALA989845 | A | Inhibition of human recombinant CYP2C9 expressed in baculovirus-infected insect microsomes | Homo sapiens | 8 | microsome format | Scientific Literature | ||
11. | ALA989846 | A | Inhibition of human recombinant CYP2C19 expressed in baculovirus-infected insect microsomes | Homo sapiens | 8 | microsome format | Scientific Literature | ||
12. | ALA989847 | A | Inhibition of human recombinant CYP2D6 expressed in baculovirus-infected insect microsomes | Homo sapiens | 8 | microsome format | Scientific Literature | ||
13. | ALA989848 | A | Inhibition of human recombinant CYP3A4 expressed in baculovirus-infected insect microsomes | Homo sapiens | 8 | microsome format | Scientific Literature | ||
14. | ALA990662 | A | Terminal half life in Wistar rat at 25 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
15. | ALA990665 | A | Tmax in Wistar rat at 25 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
16. | ALA990667 | A | Cmax in Wistar rat at 25 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
17. | ALA990669 | A | AUC (0 to infinity) in Wistar rat at 25 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
18. | ALA990672 | A | Plasma concentration in Wistar rat at 25 mg/kg, po after 0.5 to 8 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
19. | ALA990675 | F | Reduction of ACTH-induced aldosterone level in Wistar rat plasma at 20 mg/kg, iv administered before ACTH challenge after 0.5 to 3 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
20. | ALA1646710 | B | Inhibition of human aldosterone synthase expressed in chinese hamster V79 cells at 500 nM using 11-deoxycorticosterone as substrate | Homo sapiens | 23 | cell-based format | Scientific Literature |