# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA988050 | B | Inhibition of GST fused human Hdm2 assessed as polyubiquitylation by electrochemiluminescence assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
2. | ALA988055 | B | Inhibition of GST fused human Hdm2 in human RPE cells after 8 hrs by immunoblotting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA988056 | B | Inhibition of GST fused human Hdm2 in human RPE cells assessed as increase in p53 level after 8 hrs by immunoblotting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA988057 | B | Inhibition of GST fused human Hdm2 in human RPE cells at 50 uM after 8 hrs by immunoblotting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA988058 | B | Inhibition of GST fused human Hdm2 in human RPE cells assessed as increase in p53 level at 50 uM after 8 hrs by immunoblotting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA988059 | B | Inhibition of GST fused human Hdm2 expressed in p53 and mdm2-deficient mouse embryo fibroblasts under control of p53-independent promotor at 10 uM after 8 hrs by immunoblotting | Homo sapiens | 2 | assay format | Scientific Literature | ||
7. | ALA988060 | B | Inhibition of Hdm2-mediated p53 degradation in human U2-OS cells co-transfected with p53-Hdm2 after 8 hrs by immunoblotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA988061 | B | Inhibition of Hdm2-mediated p53 degradation in human U2OS cells co-transfected with p53-Hdm2 at 50 uM after 8 hrs by immunoblotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA988062 | B | Inhibition of GST fused human Hdm2 in human HCT 116 cells expressing wild type p53 assessed as prevention of N-acetyl-leucyl-leucyl-norleucinal-induced accumulation of ubiquitylated p53 accumulation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA988063 | F | Induction of apoptosis in human U2OS cells assessed as activation of p53-dependent transactivation by luciferase reporter gene assay at 1 to 10 uM after 22 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA988064 | A | Cytotoxicity against human RPE cells transformed with adenovirus E1A at 3 to 25 uM after 17 hrs by trypan blue exclusion assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA988065 | A | Cytotoxicity against p53-deficient mouse A9 cells at 5 to 20 uM after 20 hrs by trypan blue exclusion assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
13. | ALA988066 | A | Cytotoxicity against wild type p53-proficient mouse C8 cells at 5 to 20 uM after 20 hrs by trypan blue exclusion assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
14. | ALA988067 | F | Cytotoxicity against p53-deficient human HCT 116 cells at 5 to 20 uM after 20 hrs by trypan blue exclusion assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA988068 | F | Cytotoxicity against p53-proficient human HCT 116 cells at 5 to 20 uM after 20 hrs by trypan blue exclusion assay | Homo sapiens | 1 | cell-based format | Scientific Literature |