# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA984533 | Binding | Intrinsic inhibition of GST-fused human PDE4A expressed in SF9 cells | Homo sapiens | 18 | ALA1142499 | cell-based format | Scientific Literature | |
2. | ALA984534 | Functional | Inhibition of LPS-induced TNFalpha production in human whole blood | Homo sapiens | 23 | ALA1142499 | tissue-based format | Scientific Literature | |
3. | ALA984535 | Binding | Displacement of [35S]MK-499 from human ERG expressed in HEK293 cells | Homo sapiens | 23 | ALA1142499 | cell-based format | Scientific Literature | |
4. | ALA984536 | Functional | Inhibition of LPS-induced TNFalpha production in Squirrel monkey whole blood | Saimiri sciureus | 3 | ALA1142499 | tissue-based format | Scientific Literature | |
5. | ALA984537 | ADME | Inhibition of CYP2C9 | 3 | ALA1142499 | single protein format | Scientific Literature | ||
6. | ALA984538 | ADME | Half life in orally and iv dosed rat | Rattus norvegicus | 4 | ALA1142499 | organism-based format | Scientific Literature | |
7. | ALA984539 | ADME | Half life in orally and iv dosed dog | Canis lupus familiaris | 3 | ALA1142499 | organism-based format | Scientific Literature | |
8. | ALA984540 | ADME | Half life in orally and iv dosed Squirrel monkey | Saimiri sciureus | 3 | ALA1142499 | organism-based format | Scientific Literature | |
9. | ALA984541 | ADME | Cmax in po dosed squirrel monkey assessed after first episode of emesis | Saimiri sciureus | 3 | ALA1142499 | organism-based format | Scientific Literature | |
10. | ALA984542 | ADME | Bioavailability in orally and iv dosed rat | Rattus norvegicus | 3 | ALA1142499 | organism-based format | Scientific Literature | |
11. | ALA984543 | ADME | Bioavailability in orally and iv dosed dog | Canis lupus familiaris | 3 | ALA1142499 | organism-based format | Scientific Literature | |
12. | ALA984544 | ADME | Bioavailability in orally and iv dosed Squirrel monkey | Saimiri sciureus | 3 | ALA1142499 | organism-based format | Scientific Literature | |
13. | ALA984546 | Functional | Inhibition of ovalbumin-induced bronchoconstriction in conscious guinea pig at 0.03 mg/kg, ip administered 30 mins before ovalbumin challenge | Cavia porcellus | 3 | ALA1142499 | organism-based format | Scientific Literature | |
14. | ALA984547 | Functional | Inhibition of late-phase antigen-induced bronchoconstriction in ascaris-sensitive sheep at 0.5 mg/kg, iv daily for 4 days and antigen challenged after 2 hrs post dose on 4th day | Ovis aries | 3 | ALA1142499 | organism-based format | Scientific Literature | |
15. | ALA984548 | Functional | Ratio of emesis Cmax in Squirrel monkey at 2 mg/kg, po to IC50 for LPS-induced TNFalpha production in Squirrel monkey whole blood | Saimiri sciureus | 2 | ALA1142499 | organism-based format | Scientific Literature |