| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA661523 | B | Binding affinity for calf thymus DNA measured as change in melting temperature | Bos taurus | 10 | nucleic acid format | Scientific Literature | ||
| 2. | ALA665653 | B | DNA binding affinity using calf thymus DNA. | Bos taurus | 19 | nucleic acid format | Scientific Literature | ||
| 3. | ALA665654 | B | DNA binding affinity using poly(dA-dT). | 19 | nucleic acid format | Scientific Literature | |||
| 4. | ALA719973 | F | In vitro inhibitory concentration against mice infected with Trypanosoma brucei pentamidine-sensitive strain (EATRO Lab 110). | Trypanosoma brucei | 19 | organism-based format | Scientific Literature | ||
| 5. | ALA719974 | F | In vitro inhibitory concentration against mice infected with Trypanosoma brucei rhodesiense (KETRI 243). | Trypanosoma brucei | 19 | organism-based format | Scientific Literature | ||
| 6. | ALA719975 | F | In vitro inhibitory concentration against mouse infected with Trypanosoma brucei rhodesiense (KETRI 269) | Mus musculus | 14 | organism-based format | Scientific Literature | ||
| 7. | ALA719976 | F | In vitro inhibitory concentration against mouse infected with Trypanosoma brucei rhodesiense (kETRI 243As-10-3) | Trypanosoma brucei | 19 | organism-based format | Scientific Literature | ||
| 8. | ALA722434 | F | Ratio of number of cured to that of total after intraperitoneal administration (1.0 mg/kg) once a day for 3 days in mouse infected with Trypanosoma brucei (EATRO Lab 110);(0/3 of animals were cured) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA722439 | F | Ratio of number of cured to that of total after intraperitoneal administration (10.0 mg/kg) once a day for 3 days in mouse infected with Trypanosoma brucei (EATRO Lab 110); (3/3 of animals were cured) | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA722442 | F | Ratio of number of cured to that of total after intraperitoneal administration (2.5 mg/kg) once a day for 3 days in mouse infected with Trypanosoma brucei (EATRO Lab 110); (1/3 of animals were cured) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA722633 | F | Ratio of number of cured to that of total after intraperitoneal administration (25 mg/kg) once a day for 3 days in mouse infected with Trypanosoma brucei (EATRO Lab 110); (3/3 of animals were cured) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA722776 | F | Ratio of number of cured to that of total after intraperitoneal administration (5.0 mg/kg) once a day for 3 days in mouse infected with Trypanosoma brucei (EATRO Lab 110); (2/3 of animals were cured) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA883545 | B | Inhibition of [3H]dizocilpine binding to N-methyl-D-aspartate (NMDA) receptor complex in rat brain membranes | Rattus norvegicus | 14 | cell membrane format | Scientific Literature | ||
| 14. | ALA767686 | F | Anti-P. carinii activity determined as change in number of Pneumocystis carinii trophozoites from day 1 through day 5 in culture at 1 uM | Pneumocystis carinii | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA767690 | F | Percent of control growth of Pneumocystis carinii trophozoites was determined | Pneumocystis carinii | 11 | organism-based format | Scientific Literature | ||
| 16. | ALA773851 | F | Protective potency against glutamate-induced neurotoxicity in cultures of embryonic rat brain at a compound concentration of 100 uM | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA882342 | F | Protective potency against glutamate-induced neurotoxicity in cultures of embryonic rat brain at a compound concentration of 10 uM | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA773852 | F | Protective potency against glutamate-induced neurotoxicity in cultures of embryonic rat brain at a compound concentration of 10 uM+Glutamate (100 uM) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA773854 | F | Protective potency against glutamate-induced neurotoxicity in cultures of embryonic rat brain at a concentration of 100 uM+Glutamate (100 uM) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA778697 | F | Inhibitory activity (0.1 uM) against NMDA (30 uM) and glycine (10 uM) induced increase in [Ca2+]i in cultured forebrain neurons from fetal rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!