# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA941272 | B | Activation of human CAR-LBD expressed in human C3A cells at 10 uM after 24 hrs by GAL4-dependent luciferase reporter gene assay relative to control | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
2. | ALA941274 | B | Activation of human CAR Phe161Ala mutant expressed in human C3A cells at 10 uM after 24 hrs by GAL4-dependent luciferase reporter gene assay relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
3. | ALA941276 | B | Activation of human CAR Ile164Ala mutant expressed in human C3A cells at 10 uM after 24 hrs by GAL4-dependent luciferase reporter gene assay relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
4. | ALA948393 | B | Activation of human CAR His203Ala mutant expressed in human C3A cells at 10 uM after 24 hrs by GAL4-dependent luciferase reporter gene assay relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
5. | ALA948395 | B | Activation of human CAR Phe234Ala mutant expressed in human C3A cells at 10 uM after 24 hrs by GAL4-dependent luciferase reporter gene assay relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
6. | ALA948397 | B | Activation of human CAR Phe243Ala mutant expressed in human C3A cells at 10 uM after 24 hrs by GAL4-dependent luciferase reporter gene assay relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
7. | ALA948399 | B | Activation of human CAR Tyr326Ala mutant expressed in human C3A cells at 10 uM after 24 hrs by GAL4-dependent luciferase reporter gene assay relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
8. | ALA948401 | B | Increase in human steroid receptor coactivator 1 binding to human CAR-LBD expressed in human C3A cells by mammalian two-hybrid assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
9. | ALA948402 | B | Increase in human nuclear co-repressor receptor binding to human CAR-LBD expressed in HEK293 cells by yeast two-hybrid assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
10. | ALA952306 | B | Activation of human CAR Asn165Ala mutant expressed in human C3A cells at 10 uM after 24 hrs by GAL4-dependent luciferase reporter gene assay relative to control | Homo sapiens | 29 | cell-based format | Scientific Literature |