# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA948406 | F | Antagonist activity at human histamine H4 receptor expressed in HEK293 cells coexpressing G-protein assessed as inhibition of histamine-induced intracellular calcium level by FLIPR | Homo sapiens | 2 | ALA1140203 | cell-based format | Scientific Literature | |
2. | ALA948407 | F | Antagonist activity at rat histamine H4 receptor assessed as inhibition of histamine-induced intracellular calcium level by FLIPR | Rattus norvegicus | 2 | ALA1140203 | cell-based format | Scientific Literature | |
3. | ALA948408 | F | Antagonist activity at mouse histamine H4 receptor assessed as inhibition of histamine-induced intracellular calcium level by FLIPR | Mus musculus | 2 | ALA1140203 | cell-based format | Scientific Literature | |
4. | ALA948409 | F | Antagonist activity at rat histamine H4 receptor assessed as inhibition of histamine-induced [35S]GTPgamma binding | Rattus norvegicus | 1 | ALA1140203 | assay format | Scientific Literature | |
5. | ALA948410 | B | Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells by liquid scintillation counting | Homo sapiens | 2 | ALA1140203 | cell-based format | Scientific Literature | |
6. | ALA948411 | B | Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293 cells by liquid scintillation counting | Rattus norvegicus | 2 | ALA1140203 | cell-based format | Scientific Literature | |
7. | ALA948412 | B | Binding affinity to human histamine H1 receptor | Homo sapiens | 2 | ALA1140203 | single protein format | Scientific Literature | |
8. | ALA951435 | B | Binding affinity to human histamine H2 receptor | Homo sapiens | 2 | ALA1140203 | single protein format | Scientific Literature | |
9. | ALA951436 | B | Binding affinity to human histamine H3 receptor | Homo sapiens | 2 | ALA1140203 | single protein format | Scientific Literature | |
10. | ALA951437 | B | Binding affinity to rat histamine H3 receptor | Rattus norvegicus | 2 | ALA1140203 | single protein format | Scientific Literature | |
11. | ALA951438 | A | Bioavailability in Sprague-Dawley rat at 10 mg/kg, ip | Rattus norvegicus | 1 | ALA1140203 | organism-based format | Scientific Literature | |
12. | ALA951439 | A | Half life in Sprague-Dawley rat at 10 mg/kg, ip | Rattus norvegicus | 1 | ALA1140203 | organism-based format | Scientific Literature | |
13. | ALA951440 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, ip | Rattus norvegicus | 1 | ALA1140203 | organism-based format | Scientific Literature | |
14. | ALA951441 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, ip | Rattus norvegicus | 1 | ALA1140203 | organism-based format | Scientific Literature | |
15. | ALA951442 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 1 | ALA1140203 | organism-based format | Scientific Literature | |
16. | ALA951443 | A | Half life in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | ALA1140203 | organism-based format | Scientific Literature | |
17. | ALA951444 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | ALA1140203 | organism-based format | Scientific Literature | |
18. | ALA951445 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 1 | ALA1140203 | organism-based format | Scientific Literature | |
19. | ALA951446 | A | Protein binding in Sprague-Dawley rat plasma by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA1140203 | cell-free format | Scientific Literature | |
20. | ALA951447 | F | Inhibition of clobenpropit-induced itching in ip dosed CD-1(ICR) mouse administered 30 mins before clobenpropit measured for 25 mins | Mus musculus | 1 | ALA1140203 | organism-based format | Scientific Literature |