| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA999459 | B | Inhibition of Bacillus anthracis recombinant DHFR expressed in mouse M15 cells assessed as rate of enzyme-dependent NADPH oxidation | Bacillus anthracis | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA999460 | B | Inhibition of human DHFR assessed as rate of enzyme-dependent NADPH oxidation | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 3. | ALA999461 | B | Selectivity ratio of IC50 for human DHFR to IC50 for Bacillus anthracis recombinant DHFR | 16 | assay format | Scientific Literature | |||
| 4. | ALA999462 | F | Antibacterial activity against Bacillus anthracis Sterne by broth microdilution method | Bacillus anthracis | 3 | organism-based format | Scientific Literature | ||
| 5. | ALA1044821 | B | Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrate | Candida albicans | 82 | assay format | Scientific Literature | ||
| 6. | ALA1044822 | B | Inhibition of human DHFR assessed as rate of NADPH consumption using dihydrofolate as substrate | Homo sapiens | 36 | single protein format | Scientific Literature | ||
| 7. | ALA1044823 | B | Selectivity index, ratio of IC50 for human DHFR to IC50 for Candida albicans DHFR | 36 | assay format | Scientific Literature | |||
| 8. | ALA1044824 | F | Antifungal activity against Candida albicans by alamar blue assay | Candida albicans | 35 | organism-based format | Scientific Literature | ||
| 9. | ALA1044825 | A | Cytotoxicity against human MCF10A cells after 4 hrs by alamar blue assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 10. | ALA1272639 | B | Inhibition of wild type Bacillus anthracis recombinant DHFR | Bacillus anthracis | 18 | single protein format | Scientific Literature | ||
| 11. | ALA1272640 | B | Inhibition of Bacillus anthracis recombinant DHFR F96I mutant | Bacillus anthracis | 18 | assay format | Scientific Literature | ||
| 12. | ALA1272641 | B | Selectivity ratio of Ki for wild type Bacillus anthracis recombinant DHFR to Ki for Bacillus anthracis recombinant DHFR F96I mutant | Bacillus anthracis | 18 | assay format | Scientific Literature | ||
| 13. | ALA1272642 | B | Inhibition of Bacillus anthracis recombinant DHFR Y102F mutant | Bacillus anthracis | 18 | assay format | Scientific Literature | ||
| 14. | ALA1272643 | B | Selectivity ratio of Ki for wild type Bacillus anthracis recombinant DHFR to Ki for Bacillus anthracis recombinant DHFR Y102F mutant | Bacillus anthracis | 18 | assay format | Scientific Literature |
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