#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA939463	F	Antagonist activity at TLR4 in human PBMC assessed as inhibition of LPS-stimulated TNFalpha production pre-incubated for 30 mins before LPS challenge measured after 18 hrs by ELISA	Homo sapiens	4	ALA1152248	assay format	Scientific Literature
2.	ALA939464	F	Agonist activity at TLR4 in human PBMC assessed as induction of TNFalpha production after 18 hrs by sandwich ELISA	Homo sapiens	4	ALA1152248	assay format	Scientific Literature
3.	ALA939465	F	Protection against Influenza A/HK/68 virus infected BALB/c mouse assessed as survival at 5 mg/kg, intranasal administered 2 days prior to influenza challenge measured after 21 days	Influenza A virus	2	ALA1152248	organism-based format	Scientific Literature
4.	ALA939466	F	Protection against Influenza A/HK/68 virus infected BALB/c mouse assessed as survival at 0.5 mg/kg, intranasal administered 2 days prior to influenza challenge measured after 21 days	Influenza A virus	2	ALA1152248	organism-based format	Scientific Literature
5.	ALA939467	F	Protection against Influenza A/HK/68 virus infected BALB/c mouse assessed as survival at 0.05 mg/kg, intranasal administered 2 days prior to influenza challenge measured after 21 days	Influenza A virus	2	ALA1152248	organism-based format	Scientific Literature
6.	ALA939468	F	Protection against Influenza A/HK/68 virus infected BALB/c mouse assessed as survival at 0.005 mg/kg, intranasal administered 2 days prior to influenza challenge measured after 21 days	Influenza A virus	2	ALA1152248	organism-based format	Scientific Literature
7.	ALA939469	F	Protection against Listeria monocytogenes infected iv dosed BALB/c mouse assessed as reduction in splenic bacteria administered 2 days prior to bacterial challenge measured after 2 days	Listeria monocytogenes	2	ALA1152248	organism-based format	Scientific Literature
8.	ALA3373551	A	Activation of TLR4/MD2 (unknown origin) expressed in HEK293 cells co-expressing CD14 assessed as induction of MyD88-dependent NF-kappaB activity after 24 hrs by NF-kappaB SEAP reporter gene assay	Homo sapiens	11	ALA3352303	cell-based format	Scientific Literature
9.	ALA4671383	F	Induction of T-cell activation in C57BL/6 mouse assessed as induction of SIINFEKL-specific T-cell responses in blood at 5 nmol dosed intradermally	Mus musculus	5	ALA4665830	organism-based format	Scientific Literature
10.	ALA4671385	F	Induction of T-cell activation in SIINFEKL-specific mouse B3Z cells at 0.875 to 7 uM by colorimetry based in-vitro antigen presentation assay	Mus musculus	5	ALA4665830	tissue-based format	Scientific Literature
11.	ALA4671386	B	Activation of TLR4 in C57BL/6 mouse dendritic cells assessed as induction of IL-12p40 secretion at 0.098 to 100 nM incubated for 24 hrs by ELISA	Mus musculus	10	ALA4665830	tissue-based format	Scientific Literature