# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA945303 | B | Displacement of [3H]epibatidine form alpha4beta2 nAChR in rat cortex | Rattus norvegicus | 6 | ALA1152266 | assay format | Scientific Literature | |
2. | ALA945304 | B | Displacement of [3H]alpha-bungarotoxin form alpha7 nAChR in rat cortex | Rattus norvegicus | 6 | ALA1152266 | assay format | Scientific Literature | |
3. | ALA945305 | B | Selectivity ratio of Ki for rat alpha7 nAChR to Ki for rat alpha4beta2 nAChR | Rattus norvegicus | 6 | ALA1152266 | assay format | Scientific Literature | |
4. | ALA3631640 | B | Displacement of [3H]-Epibatidine from aplha6beta2* nAChR in Sprague-Dawley rat cortical membranes pre-incubated for 5 mins followed by overnight incubation by radioligand liquid scintillation counter analysis | Rattus norvegicus | 4 | ALA3627604 | assay format | Scientific Literature | |
5. | ALA3631641 | B | Displacement of [3H]-Epibatidine from human aplha3beta4 nAChR expressed in HEK293 cells pre-incubated for 5 mins followed by overnight incubation by radioligand liquid scintillation counter analysis | Homo sapiens | 4 | ALA3627604 | cell-based format | Scientific Literature | |
6. | ALA3631642 | B | Agonist activity at alpha4beta2 nAChR in Sprague-Dawley rat striatal slices assessed as increase in [3H]-Dopamine release after 5 mins by microbeta counting | Rattus norvegicus | 5 | ALA3627604 | protein complex format | Scientific Literature | |
7. | ALA3631643 | B | Agonist activity at aplha6beta2* nAChR in Sprague-Dawley rat striatal slices assessed as stinulation of [3H]-dopamine release in presence of 100 nM alpha-conotoxin MII after 5 mins by microbeta counting | Rattus norvegicus | 2 | ALA3627604 | assay format | Scientific Literature | |
8. | ALA3631754 | B | Agonist activity at alpha4beta2 nAChR in Sprague-Dawley rat striatal slices assessed as increase in [3H]-dopamine release after 5 mins by microbeta counting relative to nicotine | Rattus norvegicus | 2 | ALA3627604 | protein complex format | Scientific Literature |