# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1010709 | Functional | Cytotoxicity against human MDA-MB-231 cells after 4 days XTT assay | Homo sapiens | 35 | ALA1152785 | cell-based format | Scientific Literature | |
2. | ALA1010710 | Functional | Cytotoxicity against human MDA-MB-468 cells after 4 days by XTT assay | Homo sapiens | 35 | ALA1152785 | cell-based format | Scientific Literature | |
3. | ALA1011547 | Functional | Cytotoxicity against human HeLa cells after 4 days by XTT assay | Homo sapiens | 35 | ALA1152785 | cell-based format | Scientific Literature | |
4. | ALA1011548 | Functional | Cytotoxicity against human K562 cells after 4 days by XTT assay | Homo sapiens | 35 | ALA1152785 | cell-based format | Scientific Literature | |
5. | ALA1011550 | Binding | Binding affinity to NeK2 in human HeLa cell extract by affinity pulldown assay | Homo sapiens | 3 | ALA1152785 | cell-based format | Scientific Literature | |
6. | ALA1011552 | Functional | Anticancer activity against human HeLa cells assessed as reduction of Nek2 level at 6.25 uM by Western blot assay | Homo sapiens | 2 | ALA1152785 | cell-based format | Scientific Literature | |
7. | ALA1011553 | Functional | Anticancer activity against human HeLa cells assessed as reduction of Nek2 level at 6.25 uM after 8 to 11 hrs by Western blot assay | Homo sapiens | 2 | ALA1152785 | cell-based format | Scientific Literature | |
8. | ALA1011556 | Binding | Inhibition of Hec1/Nek2 complex in human Hela cells assessed as mitotic abnormality with multipolar spindle configuration at 3.75 uM after 24 hrs by immuno-fluorescent staining | Homo sapiens | 2 | ALA1152785 | cell-based format | Scientific Literature | |
9. | ALA1011557 | Functional | Anticancer activity against human HeLa cells expressing H2B-GFP assessed as increase in rate of chromosome misalignment at 2.5 uM after 24 hrs | Homo sapiens | 2 | ALA1152785 | cell-based format | Scientific Literature | |
10. | ALA1011558 | Functional | Induction of apoptosis in human HeLa cells assessed as morphological changes with membrane bubbling at 2.5 uM | Homo sapiens | 2 | ALA1152785 | cell-based format | Scientific Literature | |
11. | ALA1011559 | Functional | Cell cycle arrest in human HeLa cells assessed as accumulation at subG1 phase at 2.5 uM after 72 hrs by FACS analysis | Homo sapiens | 3 | ALA1152785 | cell-based format | Scientific Literature | |
12. | ALA1011560 | Binding | Inhibition of Hec1/Nek2 complex in human Hela cells assessed as mitotic abnormality with multipolar spindle configuration at 6.25 uM after 24 hrs by immuno-fluorescent staining | Homo sapiens | 2 | ALA1152785 | cell-based format | Scientific Literature |