| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1022109 | F | Agonist activity at RARbeta2 expressed in mouse NIH3T3 cells by R-SAT assay relative to Am-580 | 28 | cell-based format | Scientific Literature | |||
| 2. | ALA1022110 | F | Agonist activity at RARbeta2 expressed in mouse NIH3T3 cells by R-SAT assay | 28 | cell-based format | Scientific Literature | |||
| 3. | ALA4220761 | B | Transactivation of GST-tagged RARalpha LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by TR-FRET analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 4. | ALA4220762 | B | Transactivation of GST-tagged RARbeta LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by TR-FRET analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 5. | ALA4220763 | B | Transactivation of GST-tagged RARgamma LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by TR-FRET analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 6. | ALA4220764 | F | Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as effect on SSEA3 expression at 10 uM after 7 days by flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA4220765 | F | Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as effect on TRA160 expression at 10 uM after 7 days by flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA4220766 | F | Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as effect on A2B5 expression at 10 uM after 7 days by flow cytometric analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA4220767 | F | Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as increase in NeuroD1 mRNA expression at 10 uM by RT-PCT analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4220768 | F | Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as increase in PAX6 mRNA expression at 10 uM by RT-PCT analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4220771 | F | Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as small and scattered colonies of TUJ-1 positive cells at 10 uM measured measured after 2 weeks by immunofluorescence method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4220772 | F | Induction of neuronal differentiation in human TERA2.cl.SP12 cells assessed as increase in cytokeratin 8 expression at 10 uM measured up to 3 weeks by immunofluorescence method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4220773 | F | Induction of neuronal differentiation in human SH-SY5Y cells assessed as increase in RARalpha mRNA expression at 10 uM by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4220774 | F | Induction of neuronal differentiation in human SH-SY5Y cells assessed as increase in RARgamma mRNA expression at 10 uM by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4220775 | F | Induction of neuronal differentiation in human SH-SY5Y cells assessed as increase in RARbeta mRNA expression at 10 uM measured after 4 to 12 hrs by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4220776 | B | Transactivation of RARbeta in human SH-SY5Y cells assessed as increase in CYP26A1 mRNA expression at 10 uM measured after 4 to 12 hrs by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4220778 | F | Induction of neuronal differentiation in human SH-SY5Y cells assessed as increase in RARbeta mRNA expression at 0.001 to 1 uM measured after 8 hrs by RT-PCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4220779 | B | Transactivation of RARbeta in human SH-SY5Y cells assessed as increase in CYP26A1 mRNA expression at 0.001 to 1 uM measured after 8 hrs by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |
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