# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1034012 | Functional | Antiviral activity against influenza virus | unidentified influenza virus | 32 | ALA1136837 | organism-based format | Scientific Literature | |
2. | ALA3858688 | Binding | Inhibition of Influenza A virus A/WSN/33(H1N1) cap-dependent endonuclease using 3'-BHQ2 labeled 30-mer RNA as substrate after 60 mins by fluorescence assay | Influenza A virus (A/WSN/1933(H1N1)) | 29 | ALA3856241 | assay format | Scientific Literature | |
3. | ALA3858689 | Binding | Inhibition of Influenza A virus cap-dependent endonuclease using cap-labeled 20-mer RNA as substrate after 5 mins | Influenza A virus | 1 | ALA3856241 | assay format | Scientific Literature | |
4. | ALA2040651 | Binding | Binding affinity to PA N-terminal domain (Competitive) | Influenza A | 36 | ALA2040546 | single protein format | Scientific Literature | |
5. | ALA2040652 | Functional | Plaque growth inhibition | Canis lupus familiaris | 48 | ALA2040546 | cell-based format | Scientific Literature | |
6. | ALA2040654 | Binding | Inhibition of cap 1 ALMV primed Influenza transcriptase | Influenza A | 4 | ALA2040548 | single protein format | Scientific Literature | |
7. | ALA2040655 | Binding | Inhibition of Influenza replication | Influenza A | 4 | ALA2040548 | single protein format | Scientific Literature | |
8. | ALA2166895 | Functional | Antiviral activity against Influenza A virus assessed as inhibition of cap dependent viral transcription | Influenza A virus | 2 | ALA2163212 | organism-based format | Scientific Literature | |
9. | ALA3108108 | Binding | Inhibition of influenza A virus RNA-dependent RNA polymerase subunit PA endonuclease activity | Influenza A virus | 41 | ALA3102778 | assay format | Scientific Literature | |
10. | ALA3602688 | Binding | Inhibition of Influenza A/PR/8/34 (H1N1) core RNA-dependent RNA polymerase endonuclease activity using cap1 alfalfa mosaic virus RNA as substrate after 60 mins by liquid scintillation counting analysis in presence of [35S]-UTP | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA3600365 | assay format | Scientific Literature | |
11. | ALA3602689 | Functional | Antiviral activity against Influenza A virus (A/PR8/34(H1N1)) infected in MDCK cells assessed as inhibition of viral replication after 24 hrs | Influenza A virus | 1 | ALA3600365 | organism-based format | Scientific Literature | |
12. | ALA3625380 | Binding | Inhibition of recombinant Influenza virus A/X-31 N-terminal RdRp PA subunit (1 to 217) expressed in Escherichia coli using single-stranded circular DNA plasmid M13mp18 as substrate after 2 hrs by agarose gel electrophoresis | Influenza A virus (A/X-31(H3N2)) | 16 | ALA3621162 | assay format | Scientific Literature | |
13. | ALA3625381 | Functional | Antiviral activity against Influenza A virus (A/PR/8/1934(H1N1)) infected in MDCK cells assessed as 1-log10 reduction in viral RNA copy number after 24 hrs by quantitative RT-PCR analysis | Influenza A virus | 5 | ALA3621162 | organism-based format | Scientific Literature | |
14. | ALA3625382 | Functional | Antiviral activity against Influenza A virus (A/PR/8/1934(H1N1)) infected in MDCK cells assessed as 2-log10 reduction in viral RNA copy number after 24 hrs by quantitative RT-PCR analysis | Influenza A virus | 5 | ALA3621162 | organism-based format | Scientific Literature | |
15. | ALA3625383 | ADME | Cytotoxicity against MDCK cells assessed as cell viability measured at 24 hrs by MTS assay | Canis lupus familiaris | 5 | ALA3621162 | cell-based format | Scientific Literature | |
16. | ALA3625384 | Functional | Antiviral activity against Influenza A virus (A/PR/8/1934(H1N1)) infected in HEK293T cells assessed as reduction in viral RNP reconstitution measured at 24 hrs by luciferase reporter gene assay | Influenza A virus | 5 | ALA3621162 | organism-based format | Scientific Literature | |
17. | ALA3625385 | ADME | Cytotoxicity against HEK293T cells assessed as cell viability measured at 24 hrs by MTS assay | Homo sapiens | 5 | ALA3621162 | cell-based format | Scientific Literature | |
18. | ALA4008213 | Functional | Antiviral activity against influenza A virus (A/PR/8/34) infected in MDCK cells assessed as reduction in viral yield incubated for 30 mins prior to infection measured after 24 hrs by plaque reduction assay | Influenza A virus | 5 | ALA4007398 | cell-based format | Scientific Literature | |
19. | ALA4008214 | Binding | Inhibition of influenza A virus (A/PR/8/34) PA endonuclease using ALMV cap1 primer RNA as substrate | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 5 | ALA4007398 | single protein format | Scientific Literature | |
20. | ALA4158866 | Binding | Inhibition of Influenza A (A/California/04/2009) (H1N1) clinical isolate N-terminal truncated PA endonuclease using 5'-FAM/3-TAMRA quencer labeled 17-mer ssDNA-oligo as substrate measured over 45 mins by FRET assay | Influenza A virus (A/California/04/2009(H1N1)) | 33 | ALA4152388 | assay format | Scientific Literature |