# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1811340 | B | Displacement of [125I]-sauvagine from rat CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation counting | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
2. | ALA1006263 | A | Hepatic blood flow in iv dosed female Sprague-Dawley CD rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
3. | ALA1006264 | F | Ex vivo receptor occupancy of CRF1 receptor in po dosed Sprague-Dawley rat brain by [125I]sauvagine binding and autoradiography relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
4. | ALA985698 | B | Displacement of [125I]Tyr0-ovine CRF from CRF1 receptor in rat cortical membrane by gamma counting | Rattus norvegicus | 46 | cell membrane format | Scientific Literature | ||
5. | ALA985699 | F | Ex vivo displacement of [125I]Tyr0-ovine CRF from CRF1 receptor in dog at 5 mg/kg, po measured in plasma after 2 hrs | Canis lupus familiaris | 10 | organism-based format | Scientific Literature | ||
6. | ALA985700 | F | Ex vivo displacement of [125I]Tyr0-ovine CRF from CRF1 receptor in dog at 5 mg/kg, po measured in plasma after 10 hrs | Canis lupus familiaris | 10 | organism-based format | Scientific Literature | ||
7. | ALA985701 | B | Binding affinity to CRF1 receptor in human IMR32 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA985702 | B | Binding affinity to human CRF2alpha receptor | Homo sapiens | 4 | single protein format | Scientific Literature | ||
9. | ALA985703 | B | Binding affinity to adrenergic Alpha-1A receptor | 4 | single protein format | Scientific Literature | |||
10. | ALA985704 | B | Binding affinity to adrenergic alpha-1b receptor | 4 | single protein format | Scientific Literature | |||
11. | ALA985705 | B | Binding affinity to adrenergic alpha2b receptor | 4 | single protein format | Scientific Literature | |||
12. | ALA985706 | B | Binding affinity to adrenergic alpha2c receptor | 4 | single protein format | Scientific Literature | |||
13. | ALA985707 | B | Binding affinity to dopamine D1 receptor | 4 | single protein format | Scientific Literature | |||
14. | ALA985708 | B | Binding affinity to dopamine D2 receptor | 4 | single protein format | Scientific Literature | |||
15. | ALA985709 | B | Binding affinity to serotonin receptor | 4 | assay format | Scientific Literature | |||
16. | ALA985710 | B | Binding affinity to L-type calcium channel | 4 | assay format | Scientific Literature | |||
17. | ALA985711 | B | Binding affinity to N-type calcium channel | 4 | assay format | Scientific Literature | |||
18. | ALA985712 | B | Binding affinity to vasopressin V1 receptor | 4 | single protein format | Scientific Literature | |||
19. | ALA985713 | B | Binding affinity to human recombinant CRF binding protein | Homo sapiens | 4 | single protein format | Scientific Literature | ||
20. | ALA985714 | F | Antagonist activity at CRF1 receptor in rat brain homogenates assessed as inhibition of CRF-stimulted cAMP production | Rattus norvegicus | 5 | tissue-based format | Scientific Literature |