# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1007085 | F | Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
2. | ALA1007086 | F | Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
3. | ALA1007087 | F | Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
4. | ALA1007089 | A | Cmax in Beagle dog at 0.10 mg/kg, po by cassette assay | Canis lupus familiaris | 30 | organism-based format | Scientific Literature | ||
5. | ALA1007090 | A | AUC (0 to 24 hrs) in Beagle dog at 0.10 mg/kg, po by cassette assay | Canis lupus familiaris | 30 | organism-based format | Scientific Literature | ||
6. | ALA1007091 | A | Terminal half life in Beagle dog plasma at 0.10 mg/kg, iv by cassette assay | Canis lupus familiaris | 30 | organism-based format | Scientific Literature | ||
7. | ALA1007092 | A | Total clearance in Beagle dog at 0.10 mg/kg, iv by cassette assay | Canis lupus familiaris | 30 | organism-based format | Scientific Literature | ||
8. | ALA1007093 | A | Bioavailability in Beagle dog at 0.10 mg/kg, po and iv by cassette assay | Canis lupus familiaris | 30 | organism-based format | Scientific Literature | ||
9. | ALA1007108 | F | Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassay | Canis lupus familiaris | 17 | cell-based format | Scientific Literature | ||
10. | ALA1007109 | F | Inhibition of carbachol-induced increase in intravesical pressure in Beagle dog OAB model at 10 ug/kg, iv for 30 mins measured for 180 mins | Canis lupus familiaris | 13 | organism-based format | Scientific Literature | ||
11. | ALA1007111 | F | Inhibition of carbachol-induced increase in intravesical pressure in intraduodenally dosed Beagle dog OAB model for 30 mins measured for 180 mins | Canis lupus familiaris | 13 | organism-based format | Scientific Literature | ||
12. | ALA1002998 | F | Inhibition of KCl-induced tonic contraction in Beagle dog detrusor muscle strips preincubated for 15 mins before KCl challenge | Canis lupus familiaris | 17 | assay format | Scientific Literature | ||
13. | ALA1002999 | A | Protein binding in Beagle dog serum | Canis lupus familiaris | 13 | cell-free format | Scientific Literature | ||
14. | ALA1003000 | U | Ratio of EC50 for inhibition of KCl-induced tonic contraction in anesthetized Beagle dog detrusor muscle strip to EC50 for dog recombinant beta3 adrenergic receptor expressed in CHO cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature |