# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA984126 | Binding | Binding affinity to human PARP3 PARP domain by isothermal titration colorimetry | Homo sapiens | 4 | ALA1138469 | single protein format | Scientific Literature | |
2. | ALA984127 | Binding | Binding affinity to human PARP1 by isothermal titration colorimetry | Homo sapiens | 4 | ALA1138469 | single protein format | Scientific Literature | |
3. | ALA984130 | Binding | Binding affinity to human PARP1 | Homo sapiens | 1 | ALA1138469 | single protein format | Scientific Literature | |
4. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
5. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
6. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
7. | ALA4742558 | Binding | Inhibition of N-terminal His-tagged human PARP15 catalytic domain (481 to 678 residues) expressed in Escherichia coli BL21 (DE3) cells up to 100 uM in presence of NAD+ incubated for 2 hrs by M-ELISA plate method | Homo sapiens | 8 | ALA4742396 | cell-based format | Patent Bioactivity Data | |
8. | ALA4742559 | Binding | Dose dependent inhibition of N-terminal His-tagged human PARP14 catalytic domain 161 1611 to 1801 residues) expressed in Escherichia coli BL21 (DE3) cells up to 100 uM in presence of NAD+ incubated for 2 hrs by M-ELISA plate method | Homo sapiens | 8 | ALA4742396 | cell-based format | Patent Bioactivity Data | |
9. | ALA4808149 | Binding | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 | |
10. | ALA4808150 | Binding | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 |