# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA964235 | B | Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane at 1 uM | Cavia porcellus | 52 | cell membrane format | Scientific Literature | ||
2. | ALA963181 | B | Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane at 10 nM | Cavia porcellus | 52 | cell membrane format | Scientific Literature | ||
3. | ALA963182 | B | Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane | Cavia porcellus | 53 | cell membrane format | Scientific Literature | ||
4. | ALA963184 | F | Agonist activity at mouse 5HT4a receptor expressed in african green monkey COS7 cells assessed as cAMP release relative to serotonin | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA963185 | F | Antagonist activity at mouse 5HT4a receptor expressed in african green monkey COS7 cells assessed as inhibition of 5HT-induced cAMP release relative to serotonin | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA963186 | T | Toxicity in ip dosed NMRI mouse | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA963187 | T | Acute toxicity in NMRI mouse assessed as behavioral changes at subtoxic <1/4 dose of LD50, ip by CNS activity test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA963190 | T | Acute toxicity in NMRI mouse assessed as induction of convulsions at 100 to 300 mg/kg, ip by CNS activity test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
9. | ALA963191 | T | Toxicity in NMRI mouse assessed as spontaneous alteration performance ar 0.3 to 3 mg/kg, ip by Y-maze test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA963192 | F | Inhibition of scopolamine-induced immediate working memory deficit in NMRI mouse at 0.3 to 3 mg/kg, ip by Y-maze test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA963194 | F | Antinociceptive activity against acetic acid-induced writhing in NMRI mouse assessed as number of stretches at 0.01 mg/kg, ip by writhing test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
12. | ALA963195 | F | Antinociceptive activity against acetic acid-induced writhing in NMRI mouse assessed as number of stretches at 0.1 mg/kg, ip by writhing test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
13. | ALA963196 | F | Antinociceptive activity against acetic acid-induced writhing in NMRI mouse assessed as number of stretches at 1 mg/kg, ip by writhing test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
14. | ALA963199 | F | Analgesic activity in NMRI mouse assessed as reaction time taken to lick fore paw at 0.01 to 1 mg/kg, ip by hot plate test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA964015 | F | Antagonist activity at 5HT3 receptor in hybrid NG108-15 cells assessed as inhibition of 5HT-induced current by electrophysiology | 1 | cell-based format | Scientific Literature | |||
16. | ALA964016 | F | Antagonist activity at 5HT3 receptor in hybrid NG108-15 cells assessed as inhibition of 5HT-induced current treated 1 min prior to agonist treatment by electrophysiology | 1 | cell-based format | Scientific Literature | |||
17. | ALA964017 | B | Displacement of [3H]8OH-DPAT from human recombinant 5HT1A receptor | Homo sapiens | 3 | single protein format | Scientific Literature | ||
18. | ALA964018 | B | Displacement of [3H]5OH-tryptamine form 5HT1B receptor in rat cerebral cortex | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
19. | ALA964019 | B | Displacement of [3H]5OH-tryptamine rat recombinant 5HT1D receptor | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
20. | ALA964020 | B | Displacement of [3H]ketanserin form human recombinant 5HT2A receptor | Homo sapiens | 3 | single protein format | Scientific Literature |