# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1017182 | B | Inhibition of human VEGFR2 expressed in Sf9 cells | Homo sapiens | 33 | ALA1137777 | cell-based format | Scientific Literature | |
2. | ALA1017183 | F | Antiangiogenic activity in HUVEC assessed as inhibition of VEGF-induced cell proliferation by [3H]thymidine incorporation assay | Homo sapiens | 33 | ALA1137777 | cell-based format | Scientific Literature | |
3. | ALA1017184 | B | Inhibition of human IGFR1 | Homo sapiens | 3 | ALA1137777 | single protein format | Scientific Literature | |
4. | ALA1017185 | B | Inhibition of human InsR | Homo sapiens | 3 | ALA1137777 | single protein format | Scientific Literature | |
5. | ALA1017186 | B | Inhibition of human CDK1 | Homo sapiens | 3 | ALA1137777 | single protein format | Scientific Literature | |
6. | ALA1017187 | B | Inhibition of human CDK4 | Homo sapiens | 3 | ALA1137777 | single protein format | Scientific Literature | |
7. | ALA1017188 | B | Inhibition of human EGFR | Homo sapiens | 3 | ALA1137777 | single protein format | Scientific Literature | |
8. | ALA1017189 | B | Inhibition of human HER2 | Homo sapiens | 3 | ALA1137777 | single protein format | Scientific Literature | |
9. | ALA1017190 | B | Inhibition of human Plk1 | Homo sapiens | 3 | ALA1137777 | single protein format | Scientific Literature | |
10. | ALA1017191 | F | Antiangiogenic activity against human HeLa cells assessed as inhibition of cell proliferation by [3H]thymidine incorporation assay | Homo sapiens | 5 | ALA1137777 | cell-based format | Scientific Literature | |
11. | ALA1017192 | B | Inhibition of human FGFR1 | Homo sapiens | 18 | ALA1137777 | single protein format | Scientific Literature | |
12. | ALA1017193 | B | Inhibition of human PDGFRalpha | Homo sapiens | 18 | ALA1137777 | single protein format | Scientific Literature | |
13. | ALA1017194 | B | Inhibition of human VEGFR1 | Homo sapiens | 18 | ALA1137777 | single protein format | Scientific Literature | |
14. | ALA1017195 | B | Inhibition of human VEGFR3 | Homo sapiens | 18 | ALA1137777 | single protein format | Scientific Literature | |
15. | ALA1017196 | A | Cmax in NMRI nu/nu mouse at 50 mg/kg, po administered as single dose | Mus musculus | 2 | ALA1137777 | organism-based format | Scientific Literature | |
16. | ALA1017197 | A | Half life in NMRI nu/nu mouse at 50 mg/kg, po administered as single dose | Mus musculus | 2 | ALA1137777 | organism-based format | Scientific Literature | |
17. | ALA1017198 | A | AUC in NMRI nu/nu mouse at 50 mg/kg, po administered as single dose | Mus musculus | 2 | ALA1137777 | organism-based format | Scientific Literature | |
18. | ALA1017199 | A | Clearance in NMRI nu/nu mouse at 50 mg/kg, po or 10 mg/kg, iv administered as single dose | Mus musculus | 1 | ALA1137777 | organism-based format | Scientific Literature | |
19. | ALA1017200 | A | Volume of distribution in NMRI nu/nu mouse at 50 mg/kg, po or 10 mg/kg, iv administered as single dose | Mus musculus | 1 | ALA1137777 | organism-based format | Scientific Literature | |
20. | ALA1017201 | A | Oral bioavailability in NMRI nu/nu mouse at 50 mg/kg administered as single dose | Mus musculus | 1 | ALA1137777 | organism-based format | Scientific Literature |