# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA677750 | B | Displacement of [3H]E2 from calf uterine estrogen receptor | Bos taurus | 7 | ALA1136763 | protein format | Scientific Literature | |
2. | ALA712016 | F | Agonistic effect on estrogen receptor mediated transcriptional activation in MCF-7-2a cells at 1 uM compared to 10e-8 M estradiol | Homo sapiens | 7 | ALA1136763 | cell-based format | Scientific Literature | |
3. | ALA712018 | F | Inhibition of estradiol induced estrogen receptor transcriptional activation in MCF-7-2a cells | Homo sapiens | 7 | ALA1136763 | cell-based format | Scientific Literature | |
4. | ALA712019 | F | Inhibition of MCF-7 cell proliferation at 5 uM | Homo sapiens | 7 | ALA1136763 | cell-based format | Scientific Literature | |
5. | ALA1106108 | B | Activation of human ER in human MCF7:WS8 cells expressing estrogen responsive element by luciferase reporter gene assay | Homo sapiens | 6 | ALA1156189 | cell-based format | Scientific Literature | |
6. | ALA1106109 | F | Estrogenic activity in human ERalpha expressing MCF7:WS8 cells assessed as stimulation of cell proliferation after 7 days | Homo sapiens | 9 | ALA1156189 | assay format | Scientific Literature | |
7. | ALA1106110 | F | Antiestrogenic activity in human ERalpha expressing MCF7:WS8 cells assessed as inhibition of estradiol-induced proliferation at 1 uM after 7 days | Homo sapiens | 4 | ALA1156189 | cell-based format | Scientific Literature | |
8. | ALA1106113 | B | Estrogenic activity at wild type ER alpha expressed in T47D:C:4:2 cells coexpressing estrogen response element by duel luciferase reporter gene assay | 7 | ALA1156189 | cell-based format | Scientific Literature | ||
9. | ALA1106114 | B | Estrogenic activity at wild type ER alpha D351G mutant expressed in T47D:C:4:2 cells coexpressing estrogen response element by duel luciferase reporter gene assay | Homo sapiens | 7 | ALA1156189 | cell-based format | Scientific Literature | |
10. | ALA3295678 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in cell growth by measuring DNA level after 7 days by fluorescence analysis | Homo sapiens | 9 | ALA3286188 | cell-based format | Scientific Literature | |
11. | ALA3295682 | B | Antagonist activity at ER in human MCF7:WS8 cells assessed as inhibition of estradiol-induced cell growth by measuring DNA level after 7 days treated at highesy drug concentration by fluorescence analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
12. | ALA3295687 | B | Agonist activity at ER in rat GH3 cells assessed as increase in prolactin mRNA level at 10'-13 to 10'-6 M after 48 hrs by RT-PCR analysis relative to estradiol | Rattus norvegicus | 11 | ALA3286188 | cell-based format | Scientific Literature | |
13. | ALA3295689 | B | Antagonist activity at ER in rat GH3 cells assessed as inhibition of estradiol-induced prolactin gene expression at 10'-10 to 10'-6 M after 48 hrs by RT-PCR analysis | Rattus norvegicus | 9 | ALA3286188 | cell-based format | Scientific Literature | |
14. | ALA3295693 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in pS2 gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
15. | ALA3295694 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in GREB1 gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
16. | ALA3295695 | B | Agonist activity at ER in human MCF7:WS8 cells assessed as increase in PgR gene expression at 10'-6 M after 48 hrs by RT-PCR analysis | Homo sapiens | 8 | ALA3286188 | cell-based format | Scientific Literature | |
17. | ALA3291522 | F | Effect on ER-alpha protein level in human MCF7:WS8 cells after 24 hrs by Western blot analysis relative to control | Homo sapiens | 13 | ALA3286188 | cell-based format | Scientific Literature |