# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1019821 | B | Inhibition of NF-kappaB expressed in HEK293 cells assessed as inhibition of TNF-alpha-induced transcriptional activation at 10 uM treated 24 hrs before TNFalpha challenge measured after 20 to 24 hrs by luciferase assay relative to control | 26 | cell-based format | Scientific Literature | |||
2. | ALA1019822 | B | Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of TNF-alpha-induced transcriptional activation at 10 uM treated 24 hrs before TNFalpha challenge measured after 20 to 24 hrs by luciferase assay relative to control | 26 | cell-based format | Scientific Literature | |||
3. | ALA1019825 | F | Antiinflammatory activity in Sprague-Dawley rat assessed as protection against carrageenan-induced paw edema at 50 mg/kg, po administered 1 hr before carrageenan challenge measured after 3 hrs relative to control | Rattus norvegicus | 27 | organism-based format | Scientific Literature |