| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3436042 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
| 2. | ALA3436043 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
| 3. | ALA3436044 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
| 4. | ALA3562077 | Functional | PubChem BioAssay. High Throughput Screening for Foot and Mouth Disease Virus Antivirals. (Class of assay: confirmatory) | 69,295 | ALA1201862 | assay format | PubChem BioAssays | ||
| 5. | ALA1794308 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] | Homo sapiens | 61,908 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 6. | ALA1794375 | Binding | PUBCHEM_BIOASSAY: qHTS for inhibitors of binding or entry into cells for Marburg Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249, AID540278] | 83,389 | ALA1201862 | assay format | PubChem BioAssays | ||
| 7. | ALA1794345 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 170,142 | ALA1201862 | organism-based format | PubChem BioAssays | |
| 8. | ALA1794483 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | 114,923 | ALA1201862 | assay format | PubChem BioAssays | ||
| 9. | ALA1794580 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 130,890 | ALA1201862 | organism-based format | PubChem BioAssays | |
| 10. | ALA1794584 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | 63,980 | ALA1201862 | assay format | PubChem BioAssays | ||
| 11. | ALA1816835 | Functional | Antimalarial activity against erythrocytic stage chloroquine-sensitive Plasmodium falciparum 3D7 after 48 hrs by fluorescence spectrophotometer | Plasmodium falciparum | 22 | ALA1811834 | organism-based format | Scientific Literature | |
| 12. | ALA1816836 | Functional | Antimalarial activity against erythrocytic stage multidrug-resistant Plasmodium falciparum Dd2 after 48 hrs by fluorescence spectrophotometer | Plasmodium falciparum | 22 | ALA1811834 | organism-based format | Scientific Literature | |
| 13. | ALA1816919 | Functional | Inhibition of beta-hematine formation after 18 to 24 hrs by ferriprotoporphyrin 9 biomineralization inhibition test | 22 | ALA1811834 | assay format | Scientific Literature | ||
| 14. | ALA1816920 | ADME | Cytotoxicity against mouse macrophage J774 cells at 37 uM after 24 hrs by MTT assay | Mus musculus | 1 | ALA1811834 | cell-based format | Scientific Literature | |
| 15. | ALA1816929 | ADME | Cytotoxicity against human HepG2 cells at 37 uM after 24 hrs by MTT assay | Homo sapiens | 1 | ALA1811834 | cell-based format | Scientific Literature | |
| 16. | ALA1816938 | Functional | Antimalarial activity against Plasmodium berghei str. ANKA infected in NMRI mouse at 10 mg/kg/day, ip for three days measured on day 4 by Giemsa staining | Plasmodium berghei | 7 | ALA1811834 | organism-based format | Scientific Literature | |
| 17. | ALA1738588 | Functional | PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] | Homo sapiens | 94,040 | ALA1201862 | assay format | PubChem BioAssays | |
| 18. | ALA1738184 | Functional | PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] | Homo sapiens | 77,876 | ALA1201862 | assay format | PubChem BioAssays | |
| 19. | ALA1738442 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] | Homo sapiens | 90,358 | ALA1201862 | assay format | PubChem BioAssays | |
| 20. | ALA1054500 | Functional | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening |
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