| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3436042 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
| 2. | ALA3436043 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
| 3. | ALA3436044 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
| 4. | ALA1738352 | Functional | PUBCHEM_BIOASSAY: Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction using a Full-Length Luciferase Counterscreen assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485346, AID488776] | 20 | ALA1201862 | assay format | PubChem BioAssays | ||
| 5. | ALA1794308 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] | Homo sapiens | 61,908 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 6. | ALA1794375 | Binding | PUBCHEM_BIOASSAY: qHTS for inhibitors of binding or entry into cells for Marburg Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249, AID540278] | 83,389 | ALA1201862 | assay format | PubChem BioAssays | ||
| 7. | ALA1794483 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | 114,923 | ALA1201862 | assay format | PubChem BioAssays | ||
| 8. | ALA1794486 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] | 10,834 | ALA1201862 | assay format | PubChem BioAssays | ||
| 9. | ALA1794580 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 130,890 | ALA1201862 | organism-based format | PubChem BioAssays | |
| 10. | ALA1794584 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | 63,980 | ALA1201862 | assay format | PubChem BioAssays | ||
| 11. | ALA1613800 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] | Homo sapiens | 6,916 | ALA1201862 | assay format | PubChem BioAssays | |
| 12. | ALA1738099 | Functional | PUBCHEM_BIOASSAY: Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485346, AID488776] | Homo sapiens | 20 | ALA1201862 | assay format | PubChem BioAssays | |
| 13. | ALA1738436 | Functional | PUBCHEM_BIOASSAY: Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction in luminescent format. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485346, AID488776] | Homo sapiens | 20 | ALA1201862 | assay format | PubChem BioAssays | |
| 14. | ALA1054500 | Functional | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening | |
| 15. | ALA1054501 | Functional | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening | |
| 16. | ALA1054502 | Functional | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening | |
| 17. | ALA1054503 | Functional | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening | |
| 18. | ALA1054504 | Functional | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | Homo sapiens | 13,467 | ALA1157539 | cell-based format | GSK Malaria Screening | |
| 19. | ALA1054505 | Functional | GSK_TCMDC: Inhibition Frequency Index (IFI). The number of non-kinase HTS assays where a compound showed > 50 % inhibition, expressed as a percentage of the number of such assays in which the compound was tested | 13,467 | ALA1157539 | assay format | GSK Malaria Screening | ||
| 20. | ALA1614195 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1476 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent))] | Trypanosoma cruzi | 1,957 | ALA1201862 | assay format | PubChem BioAssays |
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