#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3819806	Binding	Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currents at 20 uM relative to control	Homo sapiens	2	ALA3817738	cell-based format	Scientific Literature
2.	ALA615141	Binding	Inhibitory activity against 15-lipoxygenase in rat polymorphonuclear leukocytes		10	ALA1125679	cell-based format	Scientific Literature
3.	ALA615252	Binding	Inhibitory activity against 12-lipoxygenase in rat platelet rich plasma		10	ALA1125679	cell-free format	Scientific Literature
4.	ALA619229	Binding	Inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes		10	ALA1125679	cell-based format	Scientific Literature
5.	ALA3132221	Functional	Antinociceptive activity in CD-1 mouse assessed as inhibition of acetic acid-induced writhing at 10 mg/kg, sc administered 15 mins before acetic acid challenge measured after 20 mins	Mus musculus	26	ALA3124774	organism-based format	Scientific Literature
6.	ALA3132222	Binding	Reversible activation of TREK1 channel (unknown origin) expressed in Xenopus oocytes assessed as channel current at 20 uM incubated for 15 mins measured post compound wash-out by two-microelectrode voltage-clamp technique	Homo sapiens	21	ALA3124774	cell-based format	Scientific Literature
7.	ALA3132223	Binding	Activation of TREK1 channel (unknown origin) expressed in Xenopus oocytes assessed as ratio of current in presence of compound to current in absence of compound at 20 uM incubated for 15 mins by two-microelectrode voltage-clamp technique	Homo sapiens	22	ALA3124774	cell-based format	Scientific Literature
8.	ALA3993349	Binding	Agonist activity at human TREK1 expressed in HEK293 cells assessed as increase in K+ current at 100 uM measured at +60 mV by whole-cell patch clamp method relative to control	Homo sapiens	29	ALA3992520	cell-based format	Scientific Literature
9.	ALA3993350	Binding	Agonist activity at TREK1 in bovine AZF cells assessed as increase in K+ current at 40 uM by whole-cell patch clamp method relative to control	Bos taurus	2	ALA3992520	cell-based format	Scientific Literature
10.	ALA3993351	Binding	Agonist activity at human TREK1 expressed in xenopus oocytes assessed as increase in K+ current at 20 uM measured at 0 mV by double microelectrode method relative to control	Homo sapiens	23	ALA3992520	cell-based format	Scientific Literature
11.	ALA3993354	Functional	Antinociceptive activity in CD1 mouse assessed as inhibition of acetic acid-induced writhes at 10 mg/kg, sc pretreated for 15 mins followed by acetic acid challenge measured within 20 mins relative to control	Mus musculus	53	ALA3992520	organism-based format	Scientific Literature
12.	ALA3993355	ADME	Half life in rat liver microsomes at 40 mM in presence of NADPH-cofactor by HPLC analysis	Rattus norvegicus	6	ALA3992520	assay format	Scientific Literature
13.	ALA3993356	ADME	Drug metabolism in rat liver microsomes assessed as (E)-2-Cyano-3-(3,4-dihydroxyphenyl)acrylic acid formation at 40 mM in presence of NADPH-cofactor measured after 24 hrs by HPLC analysis	Rattus norvegicus	1	ALA3992520	assay format	Scientific Literature
14.	ALA3993357	Functional	Antinociceptive activity in CD1 mouse assessed as increase in thermal-stimulus induced paw withdrawal latency at 60 mg/kg, sc measured after 30 mins by hot plate method relative to control	Mus musculus	56	ALA3992520	organism-based format	Scientific Literature
15.	ALA3993358	Functional	Antinociceptive activity in CD1 mouse assessed as increase in thermal-stimulus induced paw withdrawal latency at 60 mg/kg, sc measured after 45 mins by hot plate method relative to control	Mus musculus	56	ALA3992520	organism-based format	Scientific Literature