# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3412009 | F | Antiparasitic activity against promastigote form of Leishmania mexicana MHOM/BZ/61/M379 at 100 uM after 24 hrs by haemocytometer | Leishmania mexicana | 8 | organism-based format | Scientific Literature | ||
2. | ALA3412010 | F | Antiparasitic activity against promastigote form of Leishmania mexicana MHOM/BZ/61/M379 after 24 hrs by haemocytometer | Leishmania mexicana | 8 | organism-based format | Scientific Literature | ||
3. | ALA3412011 | P | Solubility of the compound in phosphate buffered saline at pH 7.4 by UV spectrophotometry | 8 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA3412012 | B | Binding affinity to Leishmania major DHFR | Leishmania major | 6 | single protein format | Scientific Literature | ||
5. | ALA3412013 | B | Binding affinity to Leishmania major pteridine reductase 1 | Leishmania major | 6 | single protein format | Scientific Literature | ||
6. | ALA3412019 | P | Retention time of the compound | 4 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA3420052 | F | Antimicrobial activity against bloodstream trypomastigote stage of Trypanosoma cruzi NINOA after 24 hrs by Brener method | Trypanosoma cruzi | 12 | organism-based format | Scientific Literature | ||
8. | ALA3420053 | F | Antimicrobial activity against bloodstream trypomastigote stage of Trypanosoma cruzi INC-5 after 24 hrs by Brener method | Trypanosoma cruzi | 12 | organism-based format | Scientific Literature | ||
9. | ALA3420054 | F | Antimicrobial activity against Leishmania mexicana MHOM/BZ/61/M379 after 24 hrs by haemocytometry | Leishmania mexicana | 12 | organism-based format | Scientific Literature | ||
10. | ALA3420055 | A | Cytotoxicity against African green monkey Vero cells after 24 hrs by MTT assay | Chlorocebus sabaeus | 11 | cell-based format | Scientific Literature | ||
11. | ALA3420056 | F | Antiplasmodial activity against Plasmodium berghei infected in CD1 mouse assessed as reduction in parasitemia at 50 mg/kg, po administered for 4 days measured on day 4 relative to vehicle-treated control | Plasmodium berghei | 11 | organism-based format | Scientific Literature | ||
12. | ALA3420057 | F | Antiplasmodial activity against Plasmodium berghei infected in CD1 mouse assessed as survival time at 50 mg/kg, po administered for 4 days measured on day 4 relative to vehicle-treated control | Plasmodium berghei | 11 | organism-based format | Scientific Literature | ||
13. | ALA3420058 | P | Antioxidant activity assessed as inhibition of ABTS free radical scavenging activity after 10 mins by spectrophotometry relative to control | 13 | small-molecule physicochemical format | Scientific Literature |