# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA679795 | B | Inhibition of ET-1 binding to Endothelin A receptor in cultured rabbit renal artery vascular smooth muscle cells | Oryctolagus cuniculus | 10 | ALA1126242 | assay format | Scientific Literature | |
2. | ALA676579 | F | Compound was evaluated for in vitro functional inhibitory potency for prevention of ET-1 induced constriction of rat aortic rings (ETA receptors); ND means No Data | 1 | ALA1130517 | assay format | Scientific Literature | ||
3. | ALA676581 | F | In vitro functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors); ND means No Data | 2 | ALA1130517 | assay format | Scientific Literature | ||
4. | ALA676101 | B | Binding affinity towards Endothelin A receptor in A10 rat thoracic aorta smooth muscle cells using [125I]ET1 as radioligand | Rattus norvegicus | 11 | ALA1125940 | tissue-based format | Scientific Literature | |
5. | ALA676107 | B | Compound was evaluated for the binding affinity to Endothelin A receptor in the rat aorta | 4 | ALA1125446 | tissue-based format | Scientific Literature | ||
6. | ALA676108 | B | Compound was evaluated for the binding affinity to Endothelin A receptor in the rat atrium | 4 | ALA1125446 | tissue-based format | Scientific Literature | ||
7. | ALA677263 | B | Binding activity to ET-B receptor on bovine cerebellum membrane | Bos taurus | 12 | ALA1130471 | tissue-based format | Scientific Literature | |
8. | ALA677265 | B | Tested for the competitive binding versus [125I]- ET-1 determined in bovine cerebrum membrane for Endothelin B receptor | Bos taurus | 8 | ALA1126560 | cell membrane format | Scientific Literature | |
9. | ALA672256 | B | Receptor binding affinity was determined against [125I]ET1 with membranes prepared from human placenta for ETB receptor | 23 | ALA1130517 | assay format | Scientific Literature | ||
10. | ALA671392 | B | Ability to inhibit [125I]ET-3 binding to the Endothelin B receptor from porcine lung membranes was evaluated | Sus scrofa | 15 | ALA1129770 | tissue-based format | Scientific Literature | |
11. | ALA677400 | B | Inhibition of ET-1 binding to Endothelin B receptor in cultured rat cerebellar membranes | Rattus norvegicus | 10 | ALA1126242 | cell membrane format | Scientific Literature | |
12. | ALA676549 | B | Compound was evaluated for the binding affinity to Endothelin B receptor in the rat cerebellum | 4 | ALA1125446 | tissue-based format | Scientific Literature | ||
13. | ALA676550 | B | Compound was evaluated for the binding affinity to Endothelin B receptor in the rat hippocampus | 4 | ALA1125446 | tissue-based format | Scientific Literature | ||
14. | ALA676553 | F | Compound was evaluated for in vitro functional inhibitory potency for prevention of sarafotoxin S6c induced constriction of rat tracheal rings (ETB receptors); ND means No Data | 1 | ALA1130517 | assay format | Scientific Literature | ||
15. | ALA676555 | F | In vitro functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETB receptors); ND means No Data | 2 | ALA1130517 | assay format | Scientific Literature | ||
16. | ALA682973 | B | Receptor binding affinity was determined in a radioligand binding assay against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected CHO cells | 3 | ALA1130517 | cell-based format | Scientific Literature | ||
17. | ALA682974 | B | Receptor binding affinity was determined against [125I]ET1 with recombinant human ETA receptor, expressed in baculovirus-infected Sf9 cells | 23 | ALA1130517 | cell-based format | Scientific Literature | ||
18. | ALA872385 | B | Tested for the competitive binding versus [125I]- ET-1 determined in porcine cardiac ventricular membrane for Endothelin A receptor | Sus scrofa | 10 | ALA1126560 | assay format | Scientific Literature | |
19. | ALA682952 | B | Ability to inhibit [125I]ET1 binding to the Endothelin A receptor from porcine lung membranes was evaluated | 14 | ALA1129770 | tissue-based format | Scientific Literature | ||
20. | ALA743808 | F | Compound induced increase in cystolic free ca+2 concentration in murine peritoneal macrophages was measured | Mus musculus | 5 | ALA1126560 | organism-based format | Scientific Literature |