| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1054500 | F | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening | |
| 2. | ALA1054501 | F | GSK_TCMDC: Inhibition of Plasmodium falciparum Dd2 in whole red blood cells, using parasite LDH activity as an index of growth. Test compounds present at 2uM | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening | |
| 3. | ALA1054502 | F | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 LDH activity, using an LDH reporter assay. Test compounds present at 2uM | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening | |
| 4. | ALA1054503 | F | GSK_TCMDC: Inhibition of Plasmodium falciparum 3D7 in whole erythrocytes, using parasite LDH activity as an index of growth. | Plasmodium falciparum | 13,467 | ALA1157539 | organism-based format | GSK Malaria Screening | |
| 5. | ALA1054504 | F | GSK_TCMDC: Percent inhibition of human HepG2 cell line. Test compounds present at 10uM. | Homo sapiens | 13,467 | ALA1157539 | cell-based format | GSK Malaria Screening | |
| 6. | ALA1054505 | F | GSK_TCMDC: Inhibition Frequency Index (IFI). The number of non-kinase HTS assays where a compound showed > 50 % inhibition, expressed as a percentage of the number of such assays in which the compound was tested | 13,467 | ALA1157539 | assay format | GSK Malaria Screening | ||
| 7. | ALA1614174 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) | Bacillus subtilis | 24,076 | ALA1201862 | assay format | PubChem BioAssays | |
| 8. | ALA1614250 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | Homo sapiens | 20,446 | ALA1201862 | assay format | PubChem BioAssays | |
| 9. | ALA1614388 | B | PUBCHEM_BIOASSAY: TR-FRET counterscreen for FAK inhibitors: dose-response biochemical high throughput screening assay to identify inhibitors of Proline-rich tyrosine kinase 2 (Pyk2). (Class of assay: confirmatory) [Related pubchem assays: 794, 727, 810 ] | Homo sapiens | 210 | ALA1201862 | single protein format | PubChem BioAssays | |
| 10. | ALA1614458 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] | Homo sapiens | 75,376 | ALA1201862 | assay format | PubChem BioAssays | |
| 11. | ALA1614459 | F | PUBCHEM_BIOASSAY: qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells. (Class of assay: confirmatory) | Drosophila | 88,408 | ALA1201862 | assay format | PubChem BioAssays | |
| 12. | ALA1614512 | B | PUBCHEM_BIOASSAY: MKP-3 in vitro HTS assay. (Class of assay: confirmatory) [Related pubchem assays: 1055, 566, 1052, 553, 1054 ] | Rattus norvegicus | 129 | ALA1201862 | single protein format | PubChem BioAssays | |
| 13. | ALA1614530 | F | PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] | Escherichia coli | 61,607 | ALA1201862 | assay format | PubChem BioAssays | |
| 14. | ALA1613797 | F | PUBCHEM_BIOASSAY: qHTS Assay for Anthrax Lethal Toxin Internalization. (Class of assay: confirmatory) | Bacillus anthracis str. A2012 | 6,269 | ALA1201862 | assay format | PubChem BioAssays | |
| 15. | ALA1613808 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) | Homo sapiens | 7,224 | ALA1201862 | assay format | PubChem BioAssays | |
| 16. | ALA1614195 | F | PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1476 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent))] | Trypanosoma cruzi | 1,957 | ALA1201862 | assay format | PubChem BioAssays | |
| 17. | ALA1614257 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) | Homo sapiens | 37,649 | ALA1201862 | assay format | PubChem BioAssays | |
| 18. | ALA1614410 | F | PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] | Homo sapiens | 17,175 | ALA1201862 | assay format | PubChem BioAssays | |
| 19. | ALA1614544 | F | PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) | Homo sapiens | 36,150 | ALA1201862 | assay format | PubChem BioAssays | |
| 20. | ALA1614549 | B | PUBCHEM_BIOASSAY: Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3). (Class of assay: confirmatory) [Related pubchem assays: 746 ] | Homo sapiens | 362 | ALA1201862 | single protein format | PubChem BioAssays |
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