| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3988182 | F | GSK PKIS2: Screen against O. lienalis microfilariae, single point, at 3.1uM to assess reduction in motility. Compounds were also tested for cytotoxicity against Rhesus Monkey LLCMK2 cells. A score was assigned as follows: Score 3 = Good activity, 100 % motility reduction; Score 2 = Marginal/moderate activity, 50-99% motility reduction; Score 1 = Inactive, <50% motility reduction; Score 0 = Cytotoxic. | Onchocerca lienalis | 486 | cell-based format | Published Kinase Inhibitor Set 2 | ||
| 2. | ALA4387620 | A | Cytotoxicity in human WS1 cells assessed as reduction in cell viability incubated fro 48 hrs by alamar blue dye based assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 3. | ALA4387621 | F | Anti-tubercular activity against Mycobacterium tuberculosis H37Rv expressing LuxABCDE assessed as relative luminescence by measuring ratio of RLU (test compound)/RLU(no compound) at 1.25 uM by luminescence based assay | Mycobacterium tuberculosis | 21 | organism-based format | Scientific Literature | ||
| 4. | ALA4387622 | F | Anti-tubercular activity against Mycobacterium tuberculosis H37Rv expressing LuxABCDE assessed as relative luminescence by measuring ratio of RLU (test compound)/RLU(no compound) at 2.5 uM by luminescence based assay | Mycobacterium tuberculosis | 21 | organism-based format | Scientific Literature | ||
| 5. | ALA4387623 | F | Anti-tubercular activity against Mycobacterium tuberculosis H37Rv expressing LuxABCDE assessed as relative luminescence by measuring ratio of RLU (test compound)/RLU(no compound) at 5 uM by luminescence based assay | Mycobacterium tuberculosis | 37 | organism-based format | Scientific Literature | ||
| 6. | ALA4387624 | F | Anti-tubercular activity against Mycobacterium tuberculosis H37Rv expressing LuxABCDE assessed as relative luminescence by measuring ratio of RLU (test compound)/RLU(no compound) at 10 uM by luminescence based assay | Mycobacterium tuberculosis | 37 | organism-based format | Scientific Literature | ||
| 7. | ALA4387625 | F | Anti-tubercular activity against Mycobacterium tuberculosis H37Rv expressing LuxABCDE assessed as relative luminescence by measuring ratio of RLU (test compound)/RLU(no compound) at 20 uM by luminescence based assay | Mycobacterium tuberculosis | 37 | organism-based format | Scientific Literature |
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