# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA895231 | B | Inhibition of human recombinant renin at pH 7.2 after 1 hr by radioimmunoassay method | Homo sapiens | 53 | single protein format | Scientific Literature | ||
2. | ALA895232 | B | Inhibition of human plasma renin after 1 hr by radioimmunoassay method | Homo sapiens | 53 | cell-free format | Scientific Literature | ||
3. | ALA895233 | B | Inhibition of marmoset plasma renin after 1 hr by radioimmunoassay method | Callithrix jacchus | 53 | cell-free format | Scientific Literature | ||
4. | ALA895234 | P | Partition coefficient, log P at pH 7.4 | 1 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA895235 | P | Solubility in phosphate buffer at pH 7.0 | 1 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA895236 | P | Solubility in phosphate buffer at pH 6.0 | 1 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA895237 | P | Dissociation constant, pKa of the compound | 1 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA895238 | A | Oral bioavailability in marmoset at 3 mg/kg, iv | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
9. | ALA895239 | A | Oral bioavailability in marmoset at 10 mg/kg, po | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
10. | ALA895240 | A | Terminal half life in marmoset | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
11. | ALA895241 | A | Volume of distribution at steady state in marmoset | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
12. | ALA895242 | A | Plasma clearance in marmoset | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
13. | ALA895243 | F | Reduction in mean arterial pressure in sodium depleted marmoset at 3 mg/kg, po relative to control | Callithrix jacchus | 6 | organism-based format | Scientific Literature | ||
14. | ALA895244 | F | Reduction in mean arterial pressure in sodium depleted marmoset at 10 mg/kg, po relative to control | Callithrix jacchus | 2 | organism-based format | Scientific Literature | ||
15. | ALA895245 | F | Inhibition of plasma renin activity in sodium depleted marmoset at 3 mg/kg, po after 6 hrs | Callithrix jacchus | 5 | organism-based format | Scientific Literature | ||
16. | ALA895247 | F | Reduction in mean arterial pressure in sodium depleted marmoset after 24 hrs | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
17. | ALA895248 | F | Inhibition of plasma renin activity in sodium depleted marmoset at 30 mg/kg after 24 hrs | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
18. | ALA895249 | F | Inhibition of plasma renin activity in sodium depleted marmoset at 10 mg/kg after 24 hrs | Callithrix jacchus | 1 | organism-based format | Scientific Literature | ||
19. | ALA895250 | B | Inhibition of pig pepsin at 10 uM | Sus scrofa | 49 | assay format | Scientific Literature | ||
20. | ALA895251 | B | Inhibition of bovine cathepsin D at 10 uM | Bos taurus | 49 | single protein format | Scientific Literature |