# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA895231 | Binding | Inhibition of human recombinant renin at pH 7.2 after 1 hr by radioimmunoassay method | Homo sapiens | 53 | ALA1148800 | single protein format | Scientific Literature | |
2. | ALA895232 | Binding | Inhibition of human plasma renin after 1 hr by radioimmunoassay method | Homo sapiens | 53 | ALA1148800 | cell-free format | Scientific Literature | |
3. | ALA895233 | Binding | Inhibition of marmoset plasma renin after 1 hr by radioimmunoassay method | Callithrix jacchus | 53 | ALA1148800 | cell-free format | Scientific Literature | |
4. | ALA895234 | Physicochemical | Partition coefficient, log P at pH 7.4 | 1 | ALA1148800 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA895235 | Physicochemical | Solubility in phosphate buffer at pH 7.0 | 1 | ALA1148800 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA895236 | Physicochemical | Solubility in phosphate buffer at pH 6.0 | 1 | ALA1148800 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA895237 | Physicochemical | Dissociation constant, pKa of the compound | 1 | ALA1148800 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA895238 | ADME | Oral bioavailability in marmoset at 3 mg/kg, iv | Callithrix jacchus | 1 | ALA1148800 | organism-based format | Scientific Literature | |
9. | ALA895239 | ADME | Oral bioavailability in marmoset at 10 mg/kg, po | Callithrix jacchus | 1 | ALA1148800 | organism-based format | Scientific Literature | |
10. | ALA895240 | ADME | Terminal half life in marmoset | Callithrix jacchus | 1 | ALA1148800 | organism-based format | Scientific Literature | |
11. | ALA895241 | ADME | Volume of distribution at steady state in marmoset | Callithrix jacchus | 1 | ALA1148800 | organism-based format | Scientific Literature | |
12. | ALA895242 | ADME | Plasma clearance in marmoset | Callithrix jacchus | 1 | ALA1148800 | organism-based format | Scientific Literature | |
13. | ALA895243 | Functional | Reduction in mean arterial pressure in sodium depleted marmoset at 3 mg/kg, po relative to control | Callithrix jacchus | 6 | ALA1148800 | organism-based format | Scientific Literature | |
14. | ALA895244 | Functional | Reduction in mean arterial pressure in sodium depleted marmoset at 10 mg/kg, po relative to control | Callithrix jacchus | 2 | ALA1148800 | organism-based format | Scientific Literature | |
15. | ALA895245 | Functional | Inhibition of plasma renin activity in sodium depleted marmoset at 3 mg/kg, po after 6 hrs | Callithrix jacchus | 5 | ALA1148800 | organism-based format | Scientific Literature | |
16. | ALA895247 | Functional | Reduction in mean arterial pressure in sodium depleted marmoset after 24 hrs | Callithrix jacchus | 1 | ALA1148800 | organism-based format | Scientific Literature | |
17. | ALA895248 | Functional | Inhibition of plasma renin activity in sodium depleted marmoset at 30 mg/kg after 24 hrs | Callithrix jacchus | 1 | ALA1148800 | organism-based format | Scientific Literature | |
18. | ALA895249 | Functional | Inhibition of plasma renin activity in sodium depleted marmoset at 10 mg/kg after 24 hrs | Callithrix jacchus | 1 | ALA1148800 | organism-based format | Scientific Literature | |
19. | ALA895250 | Binding | Inhibition of pig pepsin at 10 uM | Sus scrofa | 49 | ALA1148800 | assay format | Scientific Literature | |
20. | ALA895251 | Binding | Inhibition of bovine cathepsin D at 10 uM | Bos taurus | 49 | ALA1148800 | single protein format | Scientific Literature |