| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1026212 | Binding | Reduction in human pancreatic recombinant 1B PLA2 activity expressed in Escherichia coli assessed as hydrolysis of 1,2-dimyristoyl-sn-3-glycerophosphocholine vesicles at 0.03 mol fraction relative to cholate | Homo sapiens | 18 | ALA1151805 | assay format | Scientific Literature | |
| 2. | ALA1026996 | Binding | Reduction in human pancreatic recombinant 1B PLA2 activity expressed in Escherichia coli assessed as hydrolysis of 1,2-dimyristoyl-sn-3-glycerophosphocholine vesicles at 0.007 mol fraction relative to cholate | Homo sapiens | 18 | ALA1151805 | assay format | Scientific Literature | |
| 3. | ALA1027000 | Binding | Increase in human pancreatic recombinant 1B PLA2 activity expressed in Escherichia coli assessed as hydrolysis rate of 1,2-dimyristoyl-sn-3-glycerophosphocholine vesicles in absence of cholate | Homo sapiens | 1 | ALA1151805 | assay format | Scientific Literature | |
| 4. | ALA1027001 | Binding | Reduction in human pancreatic recombinant 1B PLA2 activity expressed in Escherichia coli assessed as hydrolysis of cholate-activated 1,2-dimyristoyl-sn-3-glycerophosphocholine vesicles | Homo sapiens | 2 | ALA1151805 | assay format | Scientific Literature | |
| 5. | ALA1027002 | Binding | Apparent inhibition of human pancreatic recombinant 1B PLA2 expressed in Escherichia coli assessed as hydrolysis rate of 1,2-dimyristoyl-sn-3-glycerophosphocholine vesicles in presence of cholate | Homo sapiens | 2 | ALA1151805 | assay format | Scientific Literature | |
| 6. | ALA1027008 | Functional | Agonist activity at human FXR transfected in human HuH7 cells co-transfected with human BSEP promoter reporter plasmid at 10 uM after 30 hrs by dual-luciferase reporter assay relative to control | Homo sapiens | 10 | ALA1151805 | cell-based format | Scientific Literature | |
| 7. | ALA1027009 | Functional | Antagonist activity at human FXR transfected in human HuH7 cells co-transfected with human BSEP promoter reporter plasmid at 10 uM after 30 hrs by dual-luciferase reporter assay relative to chenodeoxycholate | Homo sapiens | 10 | ALA1151805 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!