# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1060539 | F | Inhibition of Fc-epsilonR1 expression in anti-human Fc-epsilonR1 antibody-stimulated human KU-812F cells at 50 uM after 24 hrs by flow cytometry | Homo sapiens | 1 | ALA1152932 | cell-based format | Scientific Literature | |
2. | ALA1060540 | F | Inhibition of Fc-epsilonR1 expression in anti-human Fc-epsilonR1 antibody-stimulated human KU-812F cells at 5 uM after 24 hrs by flow cytometry | Homo sapiens | 1 | ALA1152932 | cell-based format | Scientific Literature | |
3. | ALA1060541 | F | Inhibition of Fc-epsilonR1 expression in anti-human Fc-epsilonR1 antibody-stimulated human KU-812F cells at 10 uM after 24 hrs by flow cytometry | Homo sapiens | 1 | ALA1152932 | cell-based format | Scientific Literature | |
4. | ALA1060542 | F | Inhibition of Fc-epsilonR1 expression in anti-human Fc-epsilonR1 antibody-stimulated human KU-812F cells at 25 uM after 24 hrs by flow cytometry | Homo sapiens | 1 | ALA1152932 | cell-based format | Scientific Literature | |
5. | ALA1060543 | F | Inhibition of Fc-epsilonR1 protein expression in anti-human Fc-epsilonR1 antibody-stimulated human KU-812F cells after 24 hrs by Western blotting | Homo sapiens | 2 | ALA1152932 | cell-based format | Scientific Literature | |
6. | ALA1060544 | F | Inhibition of Fc-epsilonR1 alpha mRNA expression in anti-human Fc-epsilonR1 antibody-stimulated human KU-812F cells after 24 hrs by RT-PCR | Homo sapiens | 2 | ALA1152932 | cell-based format | Scientific Literature | |
7. | ALA1060545 | B | Inhibition of Fc-epsilonR1-mediated [Ca2+]i elevation in anti-human Fc-epsilonR1 antibody-stimulated human KU-812F cells | Homo sapiens | 2 | ALA1152932 | cell-based format | Scientific Literature | |
8. | ALA1060546 | B | Inhibition of Fc-epsilonR1-mediated histamine release in anti-human Fc-epsilonR1 antibody-stimulated human KU-812F cells by spectrofluorimetry | Homo sapiens | 2 | ALA1152932 | cell-based format | Scientific Literature | |
9. | ALA1060547 | A | Cytotoxicity against human KU-812F cells assessed as reduction in cell viability at 1 to 50 uM after 24 hrs by MTS assay | Homo sapiens | 2 | ALA1152932 | cell-based format | Scientific Literature | |
10. | ALA1117923 | B | Inhibition of human recombinant BACE1 after 60 mins by FRET assay | Homo sapiens | 8 | ALA1155522 | single protein format | Scientific Literature | |
11. | ALA1117924 | B | Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysis | Homo sapiens | 7 | ALA1155522 | single protein format | Scientific Literature | |
12. | ALA2394462 | B | Inhibition of SARS coronavirus 3C-like protease cis-cleavage activity transfected in african green monkey Vero cells using SAVLQSGFRK as substrate after 5 hrs by luciferase reporter gene assay | SARS coronavirus | 7 | ALA2390950 | cell-based format | Scientific Literature | |
13. | ALA2394463 | A | Cytotoxicity against african green monkey Vero cells assessed as cell death by MTT assay | Chlorocebus sabaeus | 9 | ALA2390950 | cell-based format | Scientific Literature | |
14. | ALA2395050 | F | Selectivity index, ratio of CC50 for african green monkey Vero cells to IC50 for SARS coronavirus 3C-like protease cis-cleavage activity transfected in african green monkey Vero cells | 9 | ALA2390950 | cell-based format | Scientific Literature | ||
15. | ALA2395055 | B | Competitive inhibition of C-terminal His6-tagged recombinant SARS coronavirus 3C-like protease trans-cleavage activity expressed in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQSGFRKME as substrate after 60 mins by Dixon plot analysis | SARS coronavirus | 9 | ALA2390950 | assay format | Scientific Literature | |
16. | ALA2395056 | B | Inhibition of C-terminal His6-tagged recombinant SARS coronavirus 3C-like protease trans-cleavage activity expressed in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQSGFRKME as substrate after 60 mins by FRET assay | SARS coronavirus | 9 | ALA2390950 | assay format | Scientific Literature |