# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1103007 | Binding | Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cells | Homo sapiens | 5 | ALA1154885 | cell-based format | Scientific Literature | |
2. | ALA1103009 | Binding | Inhibition of HSP90-mediated client protein HER2 degradation | 9 | ALA1154885 | single protein format | Scientific Literature | ||
3. | ALA1103015 | Binding | Binding affinity to HSP90 under reducing conditions in presence of TECP | 5 | ALA1154885 | single protein format | Scientific Literature | ||
4. | ALA1100068 | Binding | Binding affinity to HSP90 under non-reducing conditions in absence of TECP | 5 | ALA1154885 | single protein format | Scientific Literature | ||
5. | ALA1101118 | ADME | Half life in plasma of mouse bearing human MM1S cells at 50 mg/kg | Mus musculus | 1 | ALA1154885 | organism-based format | Scientific Literature | |
6. | ALA1101119 | ADME | Half life in tumor of mouse bearing human MM1S cells at 50 mg/kg | Mus musculus | 1 | ALA1154885 | organism-based format | Scientific Literature | |
7. | ALA3378861 | Functional | Increase in oxygen consumption rate/extracellular acidification rate ratio in human NCI-H1299 cells at incubated for 12 hrs | Homo sapiens | 2 | ALA3352550 | cell-based format | Scientific Literature | |
8. | ALA1026067 | ADME | Oral bioavailability in mouse | Mus musculus | 1 | ALA1158466 | organism-based format | Scientific Literature | |
9. | ALA1026068 | Binding | Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screening | Homo sapiens | 37 | ALA1158466 | cell-based format | Scientific Literature | |
10. | ALA1026070 | Binding | Binding affinity to pig spleen Hsp90 ATPase pocket by Bradford assay | Sus scrofa | 37 | ALA1158466 | tissue-based format | Scientific Literature | |
11. | ALA1026071 | Functional | Antiproliferative activity against human A375 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
12. | ALA1026072 | Functional | Antiproliferative activity against human LNCAP cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
13. | ALA1026073 | Functional | Antiproliferative activity against human MCF7 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
14. | ALA1026074 | Functional | Antiproliferative activity against human HT-29 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
15. | ALA1026075 | Functional | Antiproliferative activity against human SW620 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
16. | ALA1026851 | Functional | Antiproliferative activity against human SK-MEL-5 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
17. | ALA1026852 | Functional | Antiproliferative activity against human PC3 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
18. | ALA1026853 | Functional | Antiproliferative activity against human MDA-MB-231 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
19. | ALA1026854 | Functional | Antiproliferative activity against human NCI-H460 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature | |
20. | ALA1026855 | Functional | Antiproliferative activity against human HCT15 cells after 72 to 144 hrs by cyquant DNA dye method | Homo sapiens | 4 | ALA1158466 | cell-based format | Scientific Literature |