| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1051662 | B | Inhibition of rat recombinant PDE10A transfected in Sf9 cells | Rattus norvegicus | 18 | ALA1152448 | cell-based format | Scientific Literature | |
| 2. | ALA1827312 | B | Selectivity ratio of IC50 for rat PDE10A to IC50 for rat PDE3A | Rattus norvegicus | 4 | ALA1821671 | assay format | Scientific Literature | |
| 3. | ALA1827313 | P | Lipophilicity, log D of the compound | 4 | ALA1821671 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA1827314 | B | Inhibition of rat PDE10A | Rattus norvegicus | 4 | ALA1821671 | single protein format | Scientific Literature | |
| 5. | ALA1827315 | B | Selectivity ratio of IC50 for rat PDE10A to IC50 for rat PDE3B | Rattus norvegicus | 4 | ALA1821671 | assay format | Scientific Literature | |
| 6. | ALA1960211 | B | Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrs | Homo sapiens | 31 | ALA1955808 | single protein format | Scientific Literature | |
| 7. | ALA2187843 | F | Antihypertensive activity in Sprague-Dawley rat assessed as inhibition of monocrotaline-induced pulmonary hypertensive hemodynamic parameter at 1 ug/kg/min, sc administered through a catheter pump 3 weeks post monocrotaline challenge for 2 weeks relative to vehicle-treated control | Rattus norvegicus | 1 | ALA2177053 | organism-based format | Scientific Literature | |
| 8. | ALA2187844 | B | Selectivity ratio of IC50 for recombinant PDE11 to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 9. | ALA2187845 | B | Selectivity ratio of IC50 for recombinant PDE9A to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 10. | ALA2187846 | B | Selectivity ratio of IC50 for recombinant PDE8B to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 11. | ALA2187847 | B | Selectivity ratio of IC50 for recombinant PDE8A to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 12. | ALA2187848 | B | Selectivity ratio of IC50 for recombinant PDE7B to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 13. | ALA2187849 | B | Selectivity ratio of IC50 for recombinant PDE7A to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 14. | ALA2187850 | B | Selectivity ratio of IC50 for bovine PDE6 to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 15. | ALA2187851 | B | Selectivity ratio of IC50 for human PDE5 to IC50 for recombinant PDE10A | Homo sapiens | 1 | ALA2177053 | assay format | Scientific Literature | |
| 16. | ALA2187852 | B | Selectivity ratio of IC50 for recombinant PDE4D to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 17. | ALA2187853 | B | Selectivity ratio of IC50 for recombinant PDE4C to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 18. | ALA2187854 | B | Selectivity ratio of IC50 for recombinant PDE4B to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 19. | ALA2187855 | B | Selectivity ratio of IC50 for recombinant PDE4A to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature | ||
| 20. | ALA2187856 | B | Selectivity ratio of IC50 for recombinant PDE3B to IC50 for recombinant PDE10A | 1 | ALA2177053 | assay format | Scientific Literature |
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