# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1062746 | B | Inhibition of ALK5 expressed in CHO cells assessed as inhibition of TGF-beta-induced Smad2 phosphorylation at 1 uM | 40 | ALA1154039 | cell-based format | Scientific Literature | ||
2. | ALA1062749 | F | Cytotoxicity against human embryo lung fibrosis cells at 30 uM by MTT assay | Homo sapiens | 41 | ALA1154039 | cell-based format | Scientific Literature | |
3. | ALA1062750 | B | Inhibition of ALK4 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 0.1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
4. | ALA1062751 | B | Inhibition of ALK4 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
5. | ALA1062752 | B | Inhibition of ALK5 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 0.1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
6. | ALA1062753 | B | Inhibition of ALK5 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
7. | ALA1062754 | B | Inhibition of ALK7 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 0.1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
8. | ALA1056764 | B | Inhibition of ALK7 expressed in baculovirus/Sf9 cells assessed as inhibition of receptor autophosphorylation at 1 uM after 3 hrs | 14 | ALA1154039 | cell-based format | Scientific Literature | ||
9. | ALA1056765 | B | Selectivity for ALK5 over ALK4 | 2 | ALA1154039 | assay format | Scientific Literature | ||
10. | ALA1056766 | B | Selectivity for ALK5 over ALK7 | 2 | ALA1154039 | assay format | Scientific Literature |