# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1028679 | F | Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
2. | ALA1028680 | A | Cytotoxicity against african green monkey Vero cells | Chlorocebus sabaeus | 1 | cell-based format | Scientific Literature | ||
3. | ALA1028681 | F | Antileishmanial activity against Leishmania donovani | Leishmania donovani | 2 | organism-based format | Scientific Literature | ||
4. | ALA1028682 | F | Antitrypanosomal activity against Trypanosoma cruzi at 16.9 uM | Trypanosoma cruzi | 2 | organism-based format | Scientific Literature | ||
5. | ALA1028683 | F | Cytotoxicity against human NCI-H460 cells at 16.9 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA1028684 | F | Cytotoxicity against mouse Neuro2a cells at 16.9 uM | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA3107945 | B | Irreversible inhibition of recombinant human Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate assessed as residual activity at 10 fold IC50 preincubated for 30 mins followed by 100 fold dilution measured for 2 hrs by fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA3108093 | B | Irreversible inhibition of recombinant human Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate assessed as residual activity at 10 fold IC50 preincubated for 30 mins followed by 100 fold dilution measured immediately after dilution by fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA3108094 | B | Irreversible inhibition of recombinant human cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA3108095 | B | Selectivity index, ratio of IC50 for human Cathepsin B to IC50 for recombinant human Cathepsin L after 30 mins using Z-Phe-Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate addition | Homo sapiens | 1 | assay format | Scientific Literature | ||
11. | ALA3108096 | B | Selectivity index, ratio of IC50 for human Cathepsin B to IC50 for recombinant human Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate | Homo sapiens | 1 | assay format | Scientific Literature | ||
12. | ALA3108097 | B | Selectivity index, ratio of IC50 for human Cathepsin V to IC50 for recombinant human Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate addition | Homo sapiens | 1 | assay format | Scientific Literature | ||
13. | ALA3108098 | B | Selectivity index, ratio of IC50 for human Cathepsin V to IC50 for recombinant human Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate | Homo sapiens | 1 | assay format | Scientific Literature | ||
14. | ALA3108099 | B | Inhibition of human Cathepsin H using Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate addition | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA3108100 | B | Inhibition of human Cathepsin H using Arg-aminomethylcoumarin as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA3108101 | B | Inhibition of human Cathepsin B using Z-Phe-Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate addition | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA3108102 | B | Inhibition of human Cathepsin B using Z-Phe-Arg-aminomethylcoumarin as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA3108103 | B | Inhibition of human Cathepsin V using Z-Phe-Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate addition | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA3108104 | B | Inhibition of human Cathepsin V using Z-Phe-Arg-aminomethylcoumarin as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA3108105 | B | Inhibition of recombinant human Cathepsin L using Z-Phe-Arg-aminomethylcoumarin as substrate preincubated for 30 mins followed by substrate addition | Homo sapiens | 1 | single protein format | Scientific Literature |