# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1052341 | Functional | Antibacterial activity against permeabilized polA-deficient Bacillus anthracis Sterne assessed as inhibition of DNA replication by cell based assay | Bacillus anthracis | 18 | ALA1152954 | organism-based format | Scientific Literature | |
2. | ALA1052342 | Functional | Antibacterial activity against Bacillus anthracis Sterne by broth microdilution method | Bacillus anthracis | 18 | ALA1152954 | organism-based format | Scientific Literature | |
3. | ALA1052343 | Functional | Antibacterial activity against Staphylococcus aureus Smith by broth microdilution method | Staphylococcus aureus | 18 | ALA1152954 | organism-based format | Scientific Literature | |
4. | ALA1052344 | Binding | Inhibition of Staphylococcus aureus Smith DNA helicase DnaC assessed as strand unwinding after 30 mins by FRET assay | Staphylococcus aureus | 18 | ALA1152954 | single protein format | Scientific Literature | |
5. | ALA1052345 | Binding | Inhibition of Bacillus anthracis DNA helicase DnaB expressed in Escherichia coli BL21 (DE3) assessed as strand unwinding after 30 mins by FRET assay | Bacillus anthracis | 36 | ALA1152954 | assay format | Scientific Literature | |
6. | ALA1052358 | ADME | Cytotoxicity against human HeLa cells by MTT assay | Homo sapiens | 18 | ALA1152954 | cell-based format | Scientific Literature | |
7. | ALA1052359 | Binding | Selectivity ratio of IC50 for Staphylococcus aureus Smith DNA helicase DnaC to IC50 for Bacillus anthracis DNA helicase DnaB | 5 | ALA1152954 | assay format | Scientific Literature |